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荣誉和奖励
· 融合肝素酶及肝素酶生产低分子量肝素工艺教育部科技成果鉴定(国际先进,排名第2)(2011)
· 清华大学优秀博士毕业生、优秀博士毕业论文 (2008)
· 第十七届全国发明展览会银奖(排名第7)(2007)
· 林岛学者 (中德科学中心, 2006)
· 化学工程与生物化工年会最佳论文 (2004)
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在研课题
(1)甲醇生物合成异戊二烯途径重构,清华大学自主科研计划(项目负责人)
(2)多基因系统敲除与组合表达构建高产氢产气肠杆菌的方法研究,NSFC青年科学基金(项目负责人)
(3)甲基氧化菌甲醇生物合成异戊二烯代谢工程研究,北京市自然科学基金(项目负责人)
(4)低品位生物质碳资源的高效系统生物催化,973计划(课题骨干)
(5)智能磷酸转移酶的分子酶工程技术及其应用基础研究,NSFC重点项目(课题骨干)
(6)常压低温等离子体诱变海洋微藻的机制及其应用,日本JST-CREST项目(课题骨干)
(7)新型生物载体的制备和应用关键技术与工程示范,863计划重点项目(参加)
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代表性论文及专利
Fang, M., Wang, T., Zhang, C.*, Bai, J., Zheng, X., Zhao, X., … Xing, X.-H. Intermediate-sensor assisted push-pull strategy and its application in heterologous deoxyviolacein production in Escherichia coli. Metabolic Engineering. 2015;33, 41–51. (*corresponding)
Zhu, W.-L., Cui, J.-Y., Cui, L.-Y., Liang, W.-F., Yang, S., Zhang, C.*, & Xing, X.-H. (2015). Bioconversion of methanol to value-added mevalonate by engineered Methylobacterium extorquens AM1 containing an optimized mevalonate pathway. Applied Microbiology and Biotechnology. 2015; (*corresponding
Li, G., Zhang, C.*, & Xing, X.-H. A kinetic model for analysis of physical tunnels in sequentially acting enzymes with direct proximity channeling. Biochemical Engineering Journal. 2016;105, 242–248. (*corresponding)
Jingjun Wu, Chong Zhang, Xiang Mei, Ye Li, Xin-Hui Xing. Controllable production of low molecular weight heparins by combinations of heparinase I/II/III. Carbohydr Polym. 2014 Jan 30;101:484-92
Wu X., Zhang C., Orita I., Imanaka T., Fukui T., Xing X.-H. Thermostable alcohol dehydrogenase from Thermococcus kodakarensis KOD1 for enantioselective bioconversion of aromatic secondary alcohols. Applied and Environmental Microbiology. 2013 April; 79(7): 2209–2217.
Huang Z., Zhang C., Chen S., Ye F., Xing X.-H. Active inclusion bodies of acid phosphatase PhoC: Aggregation induced by GFP fusion and activities modulated by linker flexibility. Microbial Cell Factories. 2013 Mar 14;12:25.
Zhidan Liu, Chong Zhang, Yuan Lu, Xiao Wu, Lang Wang, Linjun Wang, Bing Han, Xin-Hui Xing, States and challenges for high-value biohythane production from waste biomass by dark fermentation technology. Bioresource Technology. 2013 May;135:292-303
Fang M., Jin L., Zhang C., Tan Y., Jiang P., Ge N., Li L., Xing X. Rapid Mutation of Spirulina platensis by a New Mutagenesis System of Atmospheric and Room Temperature Plasmas (ARTP) and Generation of a Mutant Library with Diverse Phenotypes. PLoS ONE. 2013 Oct 11;8(10):e77046
Ziliang Huang, Fengchun Ye, Chong Zhang, Shuo Chen, Yin Chen, Jingjun Wu, Masahiro Togo, Xinhui Xing. Rational Design of a Tripartite Fusion Protein of HeparinaseI Enables One-step Affinity Purification and Real-time Activity Detection. Journal of Biotechnology. 2013 Jan 10;163(1):30-7
Chong Zhang Feng-Xiang Lv and Xin-Hui Xing, Bioengineering of the Enterobacter aerogenes strain for biohydrogen production, Bioresource Technology, 2011 (accepted)
Chong Zhang and Xin-Hui Xing, Fluorescent Proteins as a Visible Molecular Signal for Rapid Quantification of Bioprocesses: Potential and Challenges, Chinese Journal of Chemical Engineering, 2010,18(5):863-869
Chong Zhang, Min-Sheng Liu, and Xin-Hui Xing, Correcting for the Inner Filter Effect in Measurements of Fluorescent Proteins in High-Cell-Density Cultures, Analytical Biochemistry, 2009,390(2):197-202
Chong Zhang, Min-Sheng Liu, and Xin-Hui Xing, Temperature Influence on Fluorescence Intensity and Enzyme Activity of the Fusion Protein of GFP and Hyperthermophilic Xylanase, Applied Microbiology and Biotechnology, 2009,84(3):511-517
Chong Zhang, Kun Ma and Xin-Hui Xing, Regulation of Hydrogen Production of Enterobacter aerogenes by External NADH and NAD+, International Journal of Hydrogen Energy, 2009,34(3):1226-1232
Chong Zhang and Xin-Hui Xing, Quantification of a specific bacterial strain in an anaerobic mixed culture for biohydrogen production by the aerobic fluorescence recovery (AFR) technique, Biochemical Engineering Journal, 2008, 39:581-585
Chong Zhang, Xin-Hui Xing and Kai Lou, Rapid detection of a gfp-marked Enterobacter aeorgenes under anaerobic conditions by aerobic fluorescence recovery, FEMS Microbiology Letters, 2005, 249:211–218
Chong Zhang, Xin-Hui Xing and Minsheng Liu, Production of multienzymes consisting of alkaline amylase and cellulase by mixed alkalophilic culture and their potential use in the saccharification of sweet potato, Biochemical Engineering Journal, 2004, 19(2):181-187
张翀, 邢新会, 一株重组产气肠杆菌Enterobacter aerogenes及其应用: 授权中国发明专利, ZL200410074437.6.
邢新会, 张翀, 吴希, 利用整细胞生物转化再生氧化型辅酶I的方法 (200810225314.6)