研究方向是围绕非活性烯烃和炔烃的不对称官能团化开展工作。以第一作者或通讯作者在国内外期刊上共发表SCI检索论文40篇如J. Am. Chem. Soc.(3篇)、Angew. Chem. Int. Ed. (9篇)、Nature Commun. (1篇)、ACS Catal. (3篇)、Chem. Commun. (4篇)、Org. Lett. (8篇)及 Chem. Eur. J. (3篇)等。其中9篇论文被Synfacts亮点评述(Synfacts 2016, 12, 86; 2015, 11, 1029; 2014,10, 1281; 2014, 10, 1272; 2014, 10, 754; 2014, 10, 530; 2013, 9, 1251; 2009, 5, 600; 2009, 5, 1363.); 2篇论文受邀收录于Emerging Investigators专刊 (Chem. Commun., 2016, 52, 9052; Org. Chem. Front., 2016, 3, 324.);4篇论文被选为封面和插图文章;2篇论文被选为热点文章;2篇论文被Organic Chemistry Portal(有机化学门户)亮点报道;1篇Org. Lett.论文在2009年被选为该杂志三年内发表的引用次数最多的20篇文章之一;1篇论文在有机化学亮点介绍 (Chin. J. Org. Chem. 2015, 35, 1802.)。引用次数达1500次;其中有三篇论文单篇引用次数达129次。
代表论文
1. Jin-Shun Lin, Xiao-Yang Dong, Tao-Tao Li, Na-Chuan Jiang, Bin Tan, and Xin-Yuan Liu* A Dual-Catalytic Strategy to Direct Asymmetric Radical Aminotrifluoromethylation of Alkenes J. Am. Chem. Soc. 2016, 138, 9357.
2. Zhi-Jia Fang, Sheng-Cai Zheng, Zhen Guo, Jing-Yao Guo, Bin Tan,* Xin-Yuan Liu*, Asymmetric Synthesis of Axially Chiral Isoquinolones: Nickel-Catalyzed Denitrogenative Transannulation Angew. Chem. Int. Ed. 2015,54, 9528.
Highlighted in Synfacts, 2015, 11, 1029.
3. Jin-Shun Lin, Peng Yu, Lin Huang, Pan Zhang, Bin Tan,* Xin-Yuan Liu*, Brønsted Acid-Catalyzed Asymmetric Hydroamination of Alkenes: Synthesis of Pyrrolidines Bearing a Tetrasubstituted Carbon Stereocenter Angew. Chem. Int. Ed. 2015, 54, 7847.
Highlighted in Chin. J. Org. Chem., 2015, 35, 1802.
4. Peng Yu, Sheng-Cai Zheng, Ning-Yuan Yang, Bin Tan,* Xin-Yuan Liu*,Phosphine-Catalyzed Remote β-C-H Functionalization of Amine Triggered by Trifluoromethylation of Alkene: One-Pot Synthesis of Bistrifluoromethylated Enamides and Oxazoles, Angew. Chem. Int. Ed. 2015, 54, 4041.
Selected as Cover Picture.
5. Peng Yu, Jin-Shun Lin, Lei Li, Sheng-Cai Zheng, Ya-Ping Xiong, Li-Jiao Zhao, Bin Tan*, and Xin-Yuan Liu*“Enantioselective C-H Bond Functionalization Triggered by Radical Trifluoromethylation of Unactivated Alkene” Angew. Chem. Int. Ed. 2014, 53, 11890.
Highlighted in Synfacts, 2014, 10, 1281.
6. Ji-Wei Zhang, Jin-Hui Xu, Dao-Juan Cheng, Chuan Shi, Xin-Yuan Liu*, Bin Tan,* Discovery and Enantiocontrol of Axially Chiral Urazoles via Organocatalytic Tyrosine Click Reaction Nature Commun. 2016,7, 10677.
7. Jian Zhang, Shao-Xia Lin, Dao-Juan Cheng, Xin-Yuan Liu*, Bin Tan,* Phosphoric Acid-Catalyzed Asymmetric Classic Passerini Reaction J. Am. Chem. Soc. 2015, 137, 14039.
Highlighted in Synfacts, 2016, 12, 86.
8. Ye-Hui Chen, Dao-Juan Cheng, Jian Zhang, Yong Wang, Xin-Yuan Liu*, Bin Tan,* Atroposelective Synthesis of Axially Chiral Biaryldiols via Organocatalytic Arylation of 2 Naphthols J. Am. Chem. Soc. 2015, 137, 15062.
9. Ming-Yue Wu, Wei-Wei He, Xin-Yuan Liu*, Bin Tan,* Asymmetric Construction of Spirooxindoles via Organocatalytic Multicomponent Reactions of Diazooxindoles Angew. Chem. Int. Ed. 2015, 54, 9409.
10. Dao-Juan Cheng, Liang Yan, Shi-Kai Tian,* Ming-Yue Wu, Lu-Xin Wang, Zi-Li Fan, Sheng-Cai Zheng, Xin-Yuan Liu,* and Bin Tan* “Highly Enantioselective Kinetic Resolution of Axially Chiral BINAM Derivatives Catalyzed by a Brønsted Acid” Angew. Chem. Int. Ed. 2014, 53, 3684.
Highlighted in Synfacts, 2014, 10, 530.
11. Ning-Yuan Yang, Zhong-Liang Li, Liu Ye, Bin Tan and Xin-Yuan Liu* Organic base-catalysed solvent-tuned chemoselective carbotrifluoromethylation and oxytrifluoromethylation of unactivated alkenes Chem. Commun., 2016, 52, 9052.
From themed collection 2016 Emerging Investigators by Chem. Commun.
12. Xiao-Long Yu, Liping Kuang, Su Chen, Xiao-Long Zhu, Zhong-Liang Li, Bin Tan, and Xin-Yuan Liu*Counteranion-Controlled Unprecedented Diastereo- and Enantioselective Tandem Povarov Reaction for Construction of Bioactive Octahydro-dipyrroloquinolines ACS Cat. 2016, in press.
13. Na Wang, Sheng-Cai Zheng, Lin-Lin Zhang, Zhen Guo* and Xin-Yuan Liu* Nickel(0)-Catalyzed Denitrogenative Transannulation of Triazoles with Alkynes: Mechanistic Insights of Chemical Reactivity, Regio- and Enantioselectivity from Density Functional Theory and Experiment ACS Cat. 2016, 6, 3496.
14. Taotao Li, Peng Yu, Jin-Shun Lin, Yonggang Zhi,* and Xin-Yuan Liu* Copper-Catalyzed Redox-Triggered Remote C-H Functionalization: Highly Selective Formation of C-CF3 and C-O Bonds Chin. J. Chem. 2016, 34, 490.
Invited paper for the Special Issue of “Trifluoromethylation and Trifluoromethythiolation Reactions”
15. Can-Liang Ma, Xiao-Hua Li, Xiao-Long Yu, Xiao-Long Zhu, Yong-Zhou Hu, Xiao-Wu Dong,* Bin Tan* andXin-Yuan Liu* Gold-catalyzed tandem synthesis of bioactive spiro-dipyrroloquinolines and its application in the one-step synthesis of incargranine B aglycone and seneciobipyrrolidine (I) Org. Chem. Front. 2016, 3, 324.
From themed collection 2015 Emerging Investigators by OCF.
16. Lin Huang, Jin-Shun Lin, Bin Tan,* Xin-Yuan Liu*, Alkene Trifluoromethylation-Initiated Remote α-Azidation of Carbonyl Compounds toward Trifluoromethyl γ-Lactam and Spirobenzofuranone-lactam ACS Cat. 2015, 5, 2826-2831.
17. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu*, Metal-Free Direct 1,6- and 1,2-Difunctionalization Triggered by Radical Trifluoromethylation of Alkenes Org. Lett. 2015, 17, 1589-1592.
18. Lin Huang, Sheng-Cai Zheng, Bin Tan,* Xin-Yuan Liu*, Trifluoromethylation-Initiated Remote Cross-Coupling of Carbonyl Compounds to Form Carbon–Heteroatom/Carbon Bonds Chem. Eur. J. 2015, 21, 6718.
19. Can-Liang Ma, Xiao-Long Yu, Xiao-Long Zhu, Yong-Zhou Hu, Xiao-Wu Dong, Bin Tan*, and Xin-Yuan Liu*“Platinum-Catalyzed Tandem Cyclization Reaction to Multiply Substituted Indolines under Microwave-Assisted Conditions” Adv. Synth. Catal. 2015, 357,569.
20. Lei Li, Jing-Yao Guo, Xing-Guo Liu, Su Chen, Yong Wang, Bin Tan*, and Xin-Yuan Liu* “Amide Groups Switch Selectivity: C-H Trifluoromethylation of α,β-Unsaturated Amides and Subsequent Asymmetric Transformation” Org. Lett., 2014, 16, 6032.
21. Jin-Shun Lin, Xiang-Geng Liu, Xiao-Long Zhu, Bin Tan,* and Xin-Yuan Liu* “Copper-Catalyzed Aminotrifluoromethylation of Unactivated Alkenes with TMSCF3: Construction of Trifluoromethylated Azaheterocycles” J. Org. Chem. 2014, 79, 7084.
22. Xing-Li Zhu, Jin-Hui Xu, Dao-Juan Cheng, Li-Jiao Zhao, Xin-Yuan Liu* and Bin Tan* “In Situ Generation of Electrophilic Trifluoromethylthio Reagents for Enantioselective Trifluoromethylthiolation of Oxindoles”Org. Lett. 2014, 16, 2192.
Highlighted in Synfacts, 2014, 10, 754.
23. Ya-Ping Xiong, Ming-Yue Wu, Xiang-Yu Zhang, Can-Liang Ma, Lin Huang, Li-Jiao Zhao, Bin Tan* and Xin-Yuan Liu* “Direct Access to α-CF3-enones via Efficient Copper-Catalyzed Trifluoromethylation of Meyer-Schuster Rearrangement” Org. Lett. 2014, 16, 1000.
This work is highlighted on the website http:// http://www.organic-chemistry.org/abstracts/lit4/389.shtm
24. Lei Li, Min Deng, Sheng-Cai Zheng, Ya-Ping Xiong, Bin Tan* and Xin-Yuan Liu* “Metal-Free Direct Intramolecular Carbotrifluoromethylation of Alkenes to Functionalized Trifluoromethyl Azaheterocycles”Org. Lett. 2014, 16, 504.
25. Jin-Shun Lin, Ya-Ping Xiong, Can-Liang Ma, Li-Jiao Zhao, Bin Tan,* and Xin-Yuan Liu* “Efficient Copper-Catalyzed Direct Intramolecular Aminotrifluoromethylation of Unactivated Alkenes with Diverse Nitrogen-Based Nucleophiles” Chem. Eur. J. 2014, 20, 1332.
26. Tao Liu, Da-Qiang Li, Si-Yu Wang Yong-Zhou Hu, Xiao-Wu Dong,* Xin-Yuan Liu,* and Chi-Ming Che “Straightforward Installation of Carbon-Halogen, Carbon-Oxygen and Carbon-Carbon Bonds within Metal–Organic Frameworks via Direct C-H Functionalization” Chem. Commun., 2014, 50,13261.
Highlighted in Synfacts, 2014, 10, 1272.
27. Tao Liu, Jin-Xin Che, Yong-Zhou Hu, Xiao-Wu Dong,* Xin-Yuan Liu,* Chi-Ming Che “Alkenyl/thiol-derived Metal–Organic Frameworks via Post-Synthetic Modification for Effective Mercury Adsorption” Chem. Eur. J.2014, 20,14090.
28. Xiao-Wu Dong, Tao Liu, Yong-Zhou Hu*, Xin-Yuan Liu*, Chi-Ming Che. Urea Postmodified in Metal-Organic Framework as Catalytically Active Hydrogen-Bond-Donating Heterogeneous Catalyst Chem. Commun., 2013, 49, 7681.
Highlighted with a front cover in Chem. Commun.;
Selected as HOT Chem. Comm. articles for May;
Highlighted in Synfacts, 2013, 9, 1251.
29. Gaosheng Yang,* Chongrong Luo, Xiaolong Mu, Tingting Wang and Xin-Yuan Liu*, Highly efficient enantioselective three-component synthesis of 2-amino-4H-chromenes catalysed by chiral tertiary amine-thioureas Chem. Commun. 2012, 48, 5880-5882.
2. Xin-Yuan Liu,[+] Zhen Guo,[+] Sijia Dong,[+] Xiao-Hua Li, and Chi-Ming Che*, “Highly efficient and diastereoselective gold(I)-catalyzed synthesis of tertiary amines from secondary amines and alkynes: substrate scope and mechanical insights” Chem. Eur. J. 2011, 17, 12932-12945. [+]denotes equal contribution
3. Ya-Ping Xiao,[+] Xin-Yuan Liu,[+] and Chi-Ming Che*, “Efficient gold(I)-catalyzed direct intramolecular hydroalkylation of unactivated alkenes with simple α-ketones” Angew. Chem. Int. Ed. 2011, 50, 4937-4941. [+]denotes equal contribution
4. Xin-Yuan Liu, Chi-Ming Che*, “Highly enantioselective synthesis of chiral secondary amines by gold(I)/chiral Brønsted acid-catalyzed tandem intermolecular hydroamination and transfer hydrogenation reactions” Org. Lett. 2009, 11, 4204-4207.
Selected by the Editorial Board of SYNFACTS and published in SYNFACTS issue 12/09.
5. Xin-Yuan Liu, Chi-Ming Che*, “Highly efficient and regioselective platinum(II)-catalyzed tandem synthesis of multiply substituted indolines and tetrahydroquinolines” Angew. Chem. Int. Ed. 2009, 48, 2367-2371.
Selected by the Editorial Board of SYNFACTS and published in SYNFACTS
issue 06/09.
6. Xin-Yuan Liu, Chi-Ming Che*, “A highly efficient and selective AuI-catalyzed tandem synthesis of diversely substituted pyrrolo[1,2-α]quinolines in aqueous medium” Angew. Chem. Int. Ed. 2008, 47, 3805-3810.
7. Xin-Yuan Liu, Pan Ding, Jie-Sheng Huang, Chi-Ming Che*, “Synthesis of substituted 1,2-dihydroquinolines and quinolines from aromatic amines and alkynes by gold(I)-catalyzed tandem hydroamination-hydroarylation under microwave-assisted conditions” Org. Lett. 2007, 9, 2645-2648.
Selected on the ACS Publications website in 2009 as Top 20 most-cited articles published in the last three years.
8. Xin-Yuan Liu, Cheng-Hui Li, Chi-Ming Che*, “Phosphine gold(I)-catalyzed hydroamination of alkenes under thermal and microwave-assisted conditions” Org. Lett. 2006, 8, 2707-2710.
Featured on the ACS Publications website as one of “Organic Letters' Hot Papers” based on citation data obtained from Thomson ISI.
Highlighted on the website http://www.organic-chemistry.org/Highlights/2007/15August.shtm