朱志，厦门大学化学化工学院特聘教授。朱志教授系厦门大学化学化工学院2011年引进的海外人才，长期从事分析化学和化学生物学的研究工作，在DNA分子工程、生物分析、生物医疗和即时检测等研究方面有着丰富的研究经验，取得了一系列创新性的研究成果，在Acc. Chem. Res.、J. Am. Chem. Soc.、Angew. Chem. Int. Ed.、Lab Chip、Anal Chem、Chem Commun等国际高水平期刊上发表论文百余篇，具有一定的国际影响力。她于2014年获得国家优秀青年科学基金的资助，荣获2016年度中国化学会青年化学奖。
朱志 通讯地址：厦门大学化学化学化工学院，邮编361005 个人简历： 2002.09-2006.07 北京大学化学与分子工程学院，学士 2006.08-2011.05 佛罗里达大学化学系，博士 2011.08-2012.01 厦门大学化学化工学院，助理教授 2012.01-2015.08 厦门大学化学化工学院，副教授 2015.08-至今 厦门大学化学化工学院，教授 2016.11-至今 厦门大学化学化工学院，特聘教授 先后获得美国化学会分析化学研究生奖、中国政府优秀自费留学生奖、国家优秀青年基金、中国化学会青年化学奖等奖项。 担任Nature子刊Scientific Reports编委，《中国化学快报》、《分析测试学报》青年编委。 研究兴趣： 生物化学及生物分析方向，包括： 1． 分子识别与传感 2． 信号放大方法 3． 微流控生物分析 近期主要代表论著： Liu, D; Jia, S; Zhang, H; Ma, Y; Guan, Z;Li, J; Zhu, Z*; Ji, T; Yang, C*. Integrating Target-Responsive Hydrogel withPressuremeter Readout Enables Simple, Sensitive, User-friendly, QuantitativePoint-of-Care Testing, ACS Appl. Mater. Interfaces, 2017, 9, 22252-22258. Zhu, Z; Yang, C. “Hydrogel DropletMicrofluidics for High-Throughput Single Molecule/Cell Analysis.” Acc. Chem.Res. 2017, 50, 22–31. Xie, Y; Wei, X; Yang, Q; Guan, Z; Liu, D;Liu, X; Zhou, L; Zhu, Z*; Lin, Z*; Yang, C*. “Shake&Read Distance-basedMicrofluidic Chip as a Portable Quantitative Readout Device for HighlySensitive Point-of-Care Testing.” Chem. Commun., 2016, 52, 13377-13380. Ma, Y; Mao, Y; Huang, D; He, Z; Yan, J;Tian, T; Shi, Y; Song, Y; Li, X; Zhu, Z*; Zhou, L; Yang, C. “Portable VisualQuantitative Detection of Aflatoxin B1 Using a Target-Responsive Hydrogel andDistance-Readout Microfluidic Chip.” Lab Chip, 2016, 16, 3097-3104. Huang, Y; Fang, L; Zhu, Z*; Ma, Y; Zhou, L;Chen, X; Xu, D; Yang, C*. “Design and synthesis of target-responsive hydrogelfor portable visual quantitative detection of uranium with a microfluidicdistance-based readout device.” Biosensors Bioelectronics, 2016, 85, 496-502. Tan, Y; Tian, T; Liu, W; Zhu, Z*; Yang, C.“Advance in phage display technology for bioanalysis.” Biotechnol J, 2016, 11,732-745. Tian, T; Li, J; Song,Y; Zhou, L; Zhu, Z*;Yang, C*. “Distance-based Microfluidic Quantitative Detection Methods forPoint-of-Care Testing.” Lab Chip, 2016, 16, 1139-1151. Zhang, W; Zu, X; Song, Y; Zhu, Z*; Yang,C*. “Detection of DNA Methyltransferase Activity using Allosteric MolecularBeacons.” Analyst, 2016, 141, 579-584. Tian, T; Wei, X; Jia, S; Zhang, R; Li, J;Zhu, Z*; Zhang, H; Ma, Y; Lin, Z; Yang, C.* “Integration of target responsiveHydrogel with cascaded enzymatic Reactions and microfluidic paper-basedanalytic Devices (μPADs) for point-of-care testing (POCT).” Biosensors Bioelectronics,2015, 77, 537-542. Zhu, Z; Guan, Z; Liu, D; Jia, S; Li, J;Lei, Z; Lin, S; Ji, T; Tian, Z; Yang, C. “TranslatingMolecular Recognition into a Pressure Signal to enable Rapid, Sensitive, andPortable Biomedical Analysis.” Angew. Chem. Int. Ed., 2015, 54, 10448-10453. (共同一作) (FrontipiecePaper) Liu, R; Huang, Y; Ma, Y; Jia, S; Gao, M;Li, J; Zhang, H; Xu, D; Wu, M; Chen, Y; Zhu, Z*; Yang C*. “Design and Synthesisof Target-Responsive Aptamer-Crosslinked Hydrogel for Visual QuantitativeDetection of Ochratoxin A.” ACS Appl. Mater. Interfaces, 2015, 7, 6982-6990. Huang, Y; Ma, Y; Chen, Y; Wu, X; Fang, L;Zhu, Z*; Yang, C*. “Target-Responsive DNAzyme Crosslinked Hydrogel for VisualQuantitative Detection of Lead.” Anal. Chem., 2014, 86, 11434–11439. Ke, G; Zhu, Z*; Wang, W; Zou, Y; Guan, Z;Jia S; Zhang, H; Wu, X; Yang, C*. “A Cell Surface-Anchored RatiometricFluorescent Probe for Extracellular pH Sensing”, ACS Applied Materials &Interfaces, 2014, 6, 15329–15334. Zhu, Z; Guan, Z; Jia, S; Lei, Z; Lin, S;Zhang, H; Ma, Y; Tian, Z-Q; Yang, C. “Au@Pt Nanoparticle EncapsulatedTarget-responsive Hydrogel with Volumetric Bar-chart Chip Readout forQuantitative Point-of-care Testing.” Angew. Chem. Int. Ed., 2014, 53, 12503–12507. (共同一作) Lin, H; Zhang, W; Jia, S; Guan, Z; Yang, C;Zhu, Z*. “Microfluidic Approaches to Rapid and Efficient Aptamer Selection.”Biomicrofluidics, 2014, 8, 041501. Zhu, Z; Song Y; Li, C; Zou, Y; Zhu, L; An,Y; Yang, C. “Monoclonal Surface Display SELEX for Simple, Rapid, Efficient andCost-Effective Aptamer Enrichment and Identification.” Anal.Chem., 2014, 86, 5881-5888. (共同一作) Lin, X; Cui, L; Huang, Y; Lin, Y; Xie, Y;Zhu, Z*; Yin, B; Chen, X; Yang, C*. “Carbon Nanoparticle-Protected Aptamers forHighly Sensitive and Selective Detection of Biomolecules Based onNuclease-Assisted Target Recycling Signal Amplification.” Chem. Commun., 2014,50, 7646-7648. Zhang, H; Song, Y; Zou, Y; Ge, Y; An, Y;Ma, Y; Zhu, Z*; Yang, C*. “A Diazirine-Based Photoaffinity Probe for Facile andEfficient Aptamer-Protein Covalent Conjugation.” Chem. Commun., 2014, 50,4891-4894. Guan, Z; Jia S; Zhu, Z; Zhang, M; Yang, C. “Facile andRapid Generation of Large-scale Micro-collagen-gel Array for Long-term SingleCell 3D Culture and Cell Proliferation Heterogeneity Analysis.” Anal. Chem.,2014, 86, 2789-2797. (共同一作) Cui, L; Zhu, Z*; Lin, L; Zhang, H; Guan, Z;Yang, C*. “Exonuclease-Assisted Cyclic Enzymatic Amplification Method Coupledwith Rolling Circle Amplification: A Dual-amplification Strategy for Sensitiveand Selective MicroRNA Detection.” Chem. Commun., 2014, 50, 1576-1578. Cui, L; Ke, G; Lin, X; Song, Y; Zhang, H;Guan, Z; Zhu, Z*; Yang, C. “Cyclic Enzymatic Amplification Method (CEAM) Basedon Exonuclease III for Highly Sensitive Bioanalysis.” Methods, 2013, 63,202-211. Cui, L; Song, Y; Ke, G; Guan, Z; Zhang, H;Lin, Y; Huang, Y; Zhu, Z*; Yang, C*. “Graphene Oxide Protected Nucleic AcidProbes for Bioanalysis and Biomedicine.” Chem. Eur. J., 2013, 19, 10442-10451. Lin, X; Zhang, C; Huang, Y; Zhu, Z*; Chen,X; Yang, C*. “Backbone-modified Molecular Beacons for highly Sensitive andSelective Detection of microRNAs Based on Duplex Specific Nuclease SignalAmplification.” Chem. Commun., 2013, 49, 7243-7245. Song, Y; Zhu, Z*; An, Y; Zhang, W; Zhang,H; Liu, D; Yu, C; Duan, W*; Yang, C*. “Selection of DNA Aptamers againstEpithelial Cell Adhesion Molecule for Cancer Imaging and Circulating Tumor CellCapturing.” Anal. Chem., 2013, 85, 4141-4149. Yan, L; Zhu, Z; Zou, Y; Huang, Y; Liu, D;Jia, S; Xu, D; Wu, M; Zhou, Y; Zhou, S; Yang, C. “Target-responsive ‘Sweet’Hydrogel with Glucometer Readout for Portable and Quantitative Detection ofNon-glucose Targets.” J. Am. Chem. Soc., 2013, 135, 3748-3751. (共同一作) (Coverpaper & JACS Spotlights) Han, D; Zhu, Z; Wu, C; Peng, L; Zhou, L;Gulbakan, B; Zhu, G; Williams, K R; Tan, W. “A Logical Molecular Circuit forProgrammable and Autonomous Regulation of Protein Activity Using DNAAptamer–Protein Interactions.” J. Am. Chem. Soc, 2012, 134, 20797-20804. (共同一作) (ACSC&EN News) Zhu, L; Li, C; Zhu, Z; Liu, D; Zou, Y;Wang, C; Fu, H; Yang, C. “In Vitro Selection of Highly Efficient G-Quadruplex-Based DNAzymes.” Anal.Chem., 2012, 84, 8383-8390. (共同一作) Wu, J; Wang, C; Li, X; Song, Y; Wang, W;Li, C; Hu, J; Zhu, Z*; Li, J; Zhang, W; Lu, Z*; Yang, C*. “Identification,Characterization and Application of a G-Quadruplex Structured DNA Aptameragainst Cancer Biomarker Protein Anterior Gradient Homolog 2.” Plos One, 2012,7, e46393. Li, C; Zhu, L; Zhu, Z; Fu, H; Jenkins, G;Wang, C; Zou, Y; Lu, X; Yang, C. “Backbone Modification Promotes Peroxidase Activity ofG-Quadruplex-Based DNAzyme.” Chem. Commun., 2012, 48, 8347-8349. (共同一作) Zhu, Z; Zhang, W; Leng, X; Zhang, M; Guan,Z; Yang, C. “Highly Sensitive and Quantitative Detection of Rare Pathogens throughAgarose Droplet Microfluidic Emulsion PCR at the Single-Cell Level.” Lab Chip,2012, 12, 3907-3913. (共同一作) Zhu, Z; Jenkins, G; Zhang, W; Zhang, M;Guan, Z; Yang, C. “Single-Molecule Emulsion PCR in Microfluidic Droplet.” Anal.Bioanal. Chem., 2012, 403, 2127-2143. Song, Y; Zhang, W; An, Y; Cui, L; Yu, C;Zhu, Z*; Yang, C*. “Label-free Visual Detection of Nucleic Acids in BiologicalSamples with Single-Base Mismatch Detection Capability.” Chem. Commun., 2012,48, 576–578. Pu, Y; Zhu, Z; Han, D; Liu, H; Liu, J;Liao, J; Zhang, K; Tan, W. “Insulin-Binding Aptamer-Conjugated Graphene Oxide for InsulinDetection.” Analyst, 2011, 47, 4138-4140. (共同一作) Wang, C; Zhu, Z; Song, Y; Lin, H; Yang, C;Tan, W. “Caged Molecular Beacons: Controlling Nucleic Acid Hybridization withLight.” Chem. Commun., 2011, 47, 5708-5710. (共同一作) Zhu, Z; Wu, C; Liu, H; Zou, Y; Zhang, X;Kang, H; Yang, C; Tan, W. “An Aptamer Cross-linked Hydrogel as a ColorimetricPlatform for Visual Detection.” Angew. Chem. Int. Ed., 2010, 49, 1052-1056.(Frontipiece Paper)
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发表于 2018-3-25 16:33:34
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