王方军,大连化物所研究员。1982年5月出生于四川省米易县,2005年毕业于浙江大学化学系,获学士学位;2011年毕业于中国科学院大连化学物理研究所,获博士学位;2010至2011年于加拿大渥太华大学系统生物学研究所联合培养;2011年获得大连化学物理研究所破格选拔“百人计划”,任副研究员;2017年任研究员。主要研究兴趣为基于液相色谱-质谱的蛋白质等生物分子及其复合物结构和相互作用表征新方法研究。曾获2012年中国科学院优秀博士学位论文;2013年UCAS-Springer优秀博士学位论文;2014年入选中国科学院青年创新促进会。
姓名:王方军
性别:男
类别:研究员
学科:分析化学
职称:研究员
学历:博士研究生
电话:0411-82464150
Email:wangfj@dicp.ac.cn
地址:大连市中山路457号
邮编:116023
研究方向:
获奖及荣誉:
代表论著:
1. Li J, Liu J, Liu Z, Tan Y, Liu X, Wang F*, Detecting Proteins Glycosylation by a Homogeneous Reaction System with Zwitterionic Gold Nanoclusters. Anal Chem. 2017, 89, 4339-4343.
2. Zhou Y, Wu Y, Yao M, Liu Z, Chen J, Chen J, Tian L, Han G, Shen JR, Wang F*. Probing the Lysine Proximal Microenvironments within Membrane Protein Complexes by Active Dimethyl Labeling and Mass Spectrometry. Anal Chem. 2016, 88, 12060-12065.
3. Chen J, Liu Z, Wang F*, Mao J, Zhou Y, Liu J, Zou H*, Zhang Y. Enhancing the performance of LC-MS for intact protein analysis by counteracting the signal suppression effects of trifluoroacetic acid during electrospray. Chem. Commun., 2015, 51, 14758-14760.
4. Li J, Wang F*, Liu J, Xiong Z, Huang G, Wan H, Liu Z, Cheng K, Zou H*. Functionalizing with glycopeptide dendrimers significantly enhances the hydrophilicity of the magnetic nanoparticles. Chem. Commun., 2015, 51, 4093-4096.
5. Liu J, Wang F*, Mao J, Zhang Z, Liu Z, Huang G, Cheng K, Zou H*. High-sensitivity N-glycoproteomic analysis of mouse brain tissue by protein extraction with a mild detergent of N-dodecyl β-D-maltoside. Anal. Chem., 2015, 87, 2054-2057.
6. Xu B, Wang F*, Song C, Sun Z, Cheng K, Tan Y, Wang H, Zou H*. Large-scale proteome quantification of hepatocellular carcinoma tissues by a three-dimensional liquid chromatography strategy integrated with sample preparation. J. Proteome Res., 2014, 13, 3645-3654.
7. Zhu J, Sun Z, Cheng K, Chen R, Ye M, Xu B, Sun D, Wang L, Liu J, Wang F*, Zou H*. Comprehensive mapping of protein N-glycosylation in human liver by combining hydrophilic interaction chromatography and hydrazide chemistry. J. Proteome Res., 2014, 13, 1713-1721.
8. Wu Y, Wang F*, Liu Z, Qin H, Song C, Huang J, Bian Y, Wei X, Dong J, Zou H*. Five-plex isotope dimethyl labeling for quantitative proteomics. Chem. Commun., 2014, 50, 1708-1710.
9. Liu J, Wang F*, Lin H, Zhu J, Bian Y, Cheng K, Zou H*. Monolithic capillary column based glycoproteomic reactor for high-sensitive analysis of N-glycoproteome. Anal. Chem., 2013, 85, 2847-2852.
10. Wang F, Song C, Cheng K, Jiang X, Ye M, Zou H*, Perspectives of comprehensive phosphoproteome analysis using shotgun strategy. Anal. Chem., 2011, 83, 8078-8085.
11. Wang F, Chen R, Zhu J, Sun D, Song C, Wu Y, Ye M, Wang L, Zou H*, A fully automated system with online sample loading, isotope dimethyl labeling and multidimensional separation for high-throughput quantitative proteome analysis. Anal. Chem., 2010, 82, 3007-3015.
12. Wang F, Dong J, Jiang X, Ye M, Zou H*, Capillary trap column with strong cation-exchange monolith for automated shotgun proteome analysis. Anal. Chem., 2007, 79, 6599-6606.
专著
1. Wang F, Applications of Monolithic Column and Isotope Dimethylation Labeling in Shotgun Proteome Analysis. Springer Theses, 2014, ISBN: 978-3-642-42007-8 (Print) 978-3-642-42008-5 (Online), DOI: 10.1007/978-3-642-42008-5.
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