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许国旺,研究员,中国科学院大连化学物理研究所生物技术部常务副主任,中国科学院分离分析化学重点实验室主任,代谢组学研究中心主任。2004年获国家自然科学基金委杰出青年基金资助。现任中国化学会色谱专业委员会主任、中国化学会质谱专业委员会副主任、中国抗癌协会肿瘤代谢委员会副主任。担任Metabolomics,Anal.Chim.Acta,Anal.Bioanal.Chem.,J.Chromatogr.B等10多个国内外杂志编委。迄今已合著5本书、在PNAS,Hepatology,Clin.Chem.,Cancer Res.,Diabetes Care,Diabetologia,Anal.Chem.等国际著名杂志发表系列文章。H-指数:55(Web of Science Core Collection)、68(Google)。申请发明专利超百件(其中50多项已授权)。研究方向包括复杂样品分离分析方法的创新性研究;代谢组学分析技术平台及其在疾病、中药、植物表型、食品安全等方面应用的研究。
姓名:许国旺
性别:男
类别:研究员;杰出青年
学科:应用化学
职称:研究员
学历: 博士研究生
电话:0411-84379530
Email:xugw@dicp.ac.cn
地址: 大连市中山路457号
邮编:116023
工作经历
1991.6-现在 大连化物所国家色谱研究分析中心工作。
1992年任气相色谱题目组副组长,94年任组长。
1995.10-1997.9 获马普(Max-Planck-Institut)研究基金在德国Tuebingen大学工作
1997年10月至今 中国科学院大连化物所研究员,生物技术部和国家色谱中心生物分子高分辨分离分析题目组组长。
1999年5月至今 中国科学院大连化物所博士生导师。
2005年7月 至今 中国科学院大连化学物理研究所代谢组学研究中心主任
工作简历
2017-03~现在, 中国科学院分离分析化学重点实验室, 主任
2016-04~现在, 中国科学院大连化学物理研究所, 生物技术部 常务副主任
2009-01~2017-03,中国科学院分离分析化学重点实验室, 副主任
2005-07~现在, 代谢组学研究中心, 主任
1997-10~现在, 中国科学院大连化学物理研究所, 高分辨分离分析及代谢组学组研究组长
1995-10~1997-09,德国Tuebingen大学, 访问学者
1994-07~1995-09,中国科学院大连化学物理研究所, 组长
1993-01~1994-06,中国科学院大连化学物理研究所, 副组长
1991-06~1992-12,中国科学院大连化学物理研究所, 职工
社会兼职
2018-12-01-2023-12-01,中国化学会色谱专业委员会, 主任
2018-02-01-今,Metabolites, 编委
2017-01-03-今,中国化学会质谱分析专业委员会, 副主任委员
2014-01-01-今,Frontiers in Molecular Biosciences, Section Metabolomics, 副编辑
2010-04-06-今,中国化学会色谱专业委员会, 副主任委员
2009-01-01-今,分析化学, 编委
2007-05-10-2014-06-11,Journal of Chromatography B, 编辑
2007-01-15-今,International Symposium on CapillaryChromatography, 国际科学委员会委员
2006-03-01-今,International Symposium on High Performance Liquid Phase Separations and Related Techniques, 国际科学委员会常务委员
1998-01-01-今,色谱, 编委
申请发明专利90多件(其中50多项已授权)。一项成果获国家科技进步二等奖(第五名),一项获辽宁省科技发明二等奖(第一名),两项成果获中国分析测试协会科学技术成果一等奖。
奖励信息
(1) 中式卷烟风格特征剖析, 一等奖, 其他, 2012
(2) 挥发性有机标记物与围手术期肝功能相关关系, 一等奖, 省级, 2011
(3) 基于色谱-质谱联用技术的代谢组学分析平台及其应用, 二等奖, 省级, 2011
(4) 工业产品中危害因子高通量表征与特征识别关键技术与应用, 二等奖, 国家级, 2011
(5) 利用化学指标体系表征卷烟产品品质特征的研究, 二等奖, 部委级, 2010
(6) 胃癌中错配修复基因功能异常的研究, 三等奖, 省级, 2010
(7) 食品、化学品中危害因子高通量表征与识别关键技术的研究及应用, 一等奖, 省级, 2010
(8) 应用全二维气相色谱技术研究卷烟烟气中化学成分, 二等奖, 部委级, 2007
(9) 气相色谱仪鉴定柱, 三等奖, 部委级, 2003
(10) 基于尿中核苷对恶性肿瘤诊断及随访的方法研究, 一等奖, 国家级, 2002
专利成果
( 1 ) 一种二维高效液相色谱装置及其应用, 发明, 2010, 第 1 作者, 专利号: ZL200610134028.X
( 2 ) 一种甲状腺疾病辅助诊断仪及其应用, 发明, 2007, 第 1 作者, 专利号: ZL200310105271.5
( 3 ) 一种气体痕量组分在色谱毛细管柱分析中的富集捕获方法, 发明, 2007, 第 5 作者, 专利号: ZL03133629.9
( 4 ) 一种CO2区域致冷的冷喷口及将该喷口用做液体CO2致冷源的阻力器, 发明, 2006, 第 5 作者, 专利号: ZL 200310119053.7
( 5 ) 用于甲烷等低碳烷烃无氧脱氢芳构化反应产物的分析方法, 发明, 2004, 第 4 作者, 专利号: ZL 98114298.2
( 6 ) 一种甲苯歧化与烷基转移反应产物的在线分析方法, 发明, 2004, 第 5 作者, 专利号: ZL 00110558.2
( 7 ) 对二甲苯液相催化氧化制对苯二甲酸反应过程产物分析方法, 发明, 2004, 第 5 作者, 专利号: ZL 99122581.3
( 8 ) 填充柱气相色谱改装装置, 实用新型, 2000, 第 5 作者, 专利号: ZL 99224545.1
( 9 ) 填充柱气相色谱改装装置, 外观设计, 2000, 第 5 作者, 专利号: ZL 99318039.6
( 10 ) 一种分析碳4烯烃的工业色谱流程及其专用仪器, 发明, 2008, 第 5 作者, 专利号: ZL200510047146.2
( 11 ) 一种改善烟草品质的方法, 发明, 2008, 第 1 作者, 专利号: ZL200410087655.3
( 12 ) 一种全二维气相色谱调制器, 发明, 2007, 第 3 作者, 专利号: ZL200410020401.x
( 13 ) 过滤、吸附及灭活病毒的纳米催化材料的快速筛选方法, 发明, 2006, 第 1 作者, 专利号: ZL 03133535.7
( 14 ) 一种用于吸附和灭活病毒的多孔固体材料及其应用, 发明, 2006, 第 4 作者, 专利号: ZL 03133534.9
( 15 ) 一种工业色谱仪模拟系统, 发明, 2006, 第 5 作者, 专利号: ZL 00123367.X
( 16 ) 一种检测血清中27-5β-降胆甾烷-3,7,12,24,25-五醇葡萄糖醛酸结合物的试剂盒及使用过程, 发明, 2010, 第 1 作者, 专利号: 201010172229.5
( 17 ) 一种卷烟品牌判别方法, 发明, 2010, 第 1 作者, 专利号: 201010238749.1
( 18 ) 一种用于研究转基因和非转基因水稻代谢差异的方法, 发明, 2010, 第 1 作者, 专利号: 201010559024.2
( 19 ) 一种检测血清中27-5β-降胆甾烷-3,7,12,24,25-五醇葡萄糖醛酸结合物的试剂盒及使用过程, 发明, 2010, 第 1 作者, 专利号: PCT/CN2010/079202
( 20 ) 一种从体液代谢组轮廓筛选糖尿病标记物的方法, 发明, 2009, 第 1 作者, 专利号: 200910248531.1
( 21 ) 一种二维高效液相色谱系统及其应用, 发明, 2011, 第 1 作者, 专利号: ZL200610134027.5
( 22 ) 烟用料液的气相色谱分析样品预处理方法, 发明, 2010, 第 1 作者, 专利号: ZL200610047016.3
( 23 ) 一种应用代谢组学对中成药质量评价的方法, 发明, 2009, 第 1 作者, 专利号: 200910248534.5
( 24 ) CO2带压净化液化的方法及装置和在区域致冷上的应用, 发明, 2007, 第 5 作者, 专利号: ZL02144879.5
( 25 ) 一种气体阻力调节器, 发明, 2004, 第 2 作者, 专利号: ZL 01133422.3
( 26 ) 微量和痕量一氧化碳、二氧化碳气相色谱分析流程, 发明, 2004, 第 2 作者, 专利号: ZL 01115824.7
( 27 ) 一种甲酰基苯硼酸修饰磁性纳米粒子及其制备和应用, 发明, 2017, 第 1 作者, 专利号: ZL 201410366030.4
( 28 ) 一种新的血清代谢物的组合及其作为肝癌诊断标志物的用途, 发明, 2017, 第 1 作者, 专利号: ZL 201410771378.1
( 29 ) 一种脂质代谢网络动态研究的方法, 发明, 2017, 第 1 作者, 专利号: ZL 201310091384.8
( 30 ) 一种判别烟草代谢组学新鲜烟叶样品质量的方法及试剂盒, 发明, 2017, 第 1 作者, 专利号: ZL201410198866.8
( 31 ) 一种五氟苄基咪唑盐离子液体杂化整体柱及其制备和应用, 发明, 2017, 第 1 作者, 专利号: 201410363663.X
( 32 ) 一种纳米硫化亚铜修饰的整体柱及其制备方法, 发明, 2017, 第 1 作者, 专利号: ZL201310646757.3
( 33 ) 苯硼酸修饰聚乙烯亚胺杂化磁性纳米粒子及其制备和应用, 发明, 2017, 第 1 作者, 专利号: ZL201310473314.9
( 34 ) 一种用于诊断肝癌的联合型代谢标志物及其检测试剂盒, 发明, 2017, 第 1 作者, 专利号: ZL201410206533.5
( 35 ) 一种基于液相色谱/质谱联用的拟靶标代谢组学分析方法, 发明, 2017, 第 1 作者, 专利号: ZL201310300518.2
( 36 ) 一种通用的大规模代谢组学数据校正方法, 发明, 2018, 第 1 作者, 专利号: 201510778032.9
( 37 ) 一种色质联用的昆虫体内保幼激素JHII的检测方法, 发明, 2018, 第 2 作者, 专利号: 201510783627.3
( 38 ) 一种同时分离代谢组和脂质组组份的液相色谱分析方法及其应用, 发明, 2018, 第 1 作者, 专利号: 201610137898.6
( 39 ) 一种高选择,高灵敏富集衍生的化学选择纳米探针及其制备方法和应用, 发明, 2018, 第 1 作者, 专利号: 201510039904.
出版信息
已发表SCI文章410多篇,包括PNAS, Hepatology, Clin. Chem., Cancer Res., Diabetes Care, Diabetologia, Anal. Chem., TrAC, J. Chromatogr. A, J. Proteome Res., Mol. Cell Proteome等国际著名杂志。H-指数: 54(Web of Science)、67 (Google)。
发表论文
(1) Comprehensive Profiling by Non-targeted Stable Isotope Tracing Capillary Electrophoresis-Mass Spectrometry - A Novel Tool Complementing Metabolomics Analyses of Polar Metabolites, Chemistry - A European Journal, 2019, 通讯作者
(2) Metabolomics profiling of metformin-mediated metabolic reprogramming bypassing AMPKα, Metabolism-Clinical and Experimental, 2019, 通讯作者
(3) Removal of False Positive Features to Generate Authentic Peak Table for High-resolution Mass Spectrometry-based Metabolomics Study, Anal. Chim. Acta, 2019, 通讯作者
(4) A comprehensive strategy for studying protein-metabolite interactions by metabolomics and native mass spectrometry, Talanta, 2019, 通讯作者
(5) Integrated metabolomics and lipidomics analyses reveal metabolic reprogramming in human glioma with IDH1 mutation, J Proteome Res., 2019, 通讯作者
(6) Modified metabolite mapping by liquid chromatography-high resolution mass spectrometry using full scan/all ion fragmentation/neutral loss acquisition, J. Chromatogr. A, 2019, 其他(合作组作者)
(7) ORP4L Extracts and Presents PIP2 from Plasma Membrane for PLCβ3 Catalysis: Targeting It Eradicates Leukemia Stem Cells, Cell Research, 2019, 其他(合作组作者)
(8) Stress-induced epinephrine enhances lactate dehydrogenase A and promotes breast cancer stem-like cells, J Clin Invest., 2019, 其他(合作组作者)
(9) Metabolic phenotypes and the gut microbiota in response to dietary resistant starch type 2 in normal-weight subjects: a randomized crossover trial, Scientific Reports, 2019, 通讯作者
(10) Serum Metabolomics Study of Non-Smoking Female Patients with Non-Small Cell Lung Cancer Using a Gas Chromatography−Mass Spectrometry, J. Proteome Res., 2019, 通讯作者
(11) Carboxymethylated Polyethylenimine Modified Magnetic Nanoparticles for Specifically Purification of His-tagged Protein, J. Sep. Sci, 2019, 其他(合作组作者)
(12) Metabolomics and transcriptomics profiles reveal thedysregulation of the tricarboxylic acid cycle and relatedmechanisms in prostate cancer, International journal of cancer, 2018, 通讯作者
(13) A Large-scale, multicenter serum metabolite biomarker identification study for the early detection of hepatocellular carcinoma, HEPATOLOGY, 2018, 通讯作者
(14) Determination of candidate metabolite biomarkers associated with recurrence of HCV-related hepatocellular carcinoma, Oncotarget, 2018, 通讯作者
(15) Global Metabolic Profiling Identifies a Pivotal Role of Proline and Hydroxyproline Metabolism in Supporting Hypoxic Response in Hepatocellular Carcinoma, CLINICAL CANCER RESEARCH, 2018, 通讯作者
(16) Molecular interaction study of flavonoids with human serum albumin using native mass spectrometry and molecular modeling, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2018, 通讯作者
(17) Metabolic changes in primary, secondary, and lipid metabolism in tobacco leaf in response to topping, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2018, 通讯作者
(18) Activation of choline kinase drives aberrant choline metabolism in esophageal squamous cell carcinomas, Journal of pharmaceutical and biomedical analysis, 2018, 通讯作者
(19) A High-Fat Diet Rich in Saturated and Mono-Unsaturated Fatty Acids Induces Disturbance of Thyroid Lipid Profile and Hypothyroxinemia in Male Rats, MOLECULAR NUTRITION & FOOD RESEARCH, 2018, 第 4 作者
(20) A high throughput metabolomics method and its application in female serum samples in a normal menstrual cycle based on liquid chromatography-mass spectrometry, Talanta, 2018, 通讯作者
(21) Synthesis of magnetic mesoporous Fe3O4@PEI-MOF-5 for the effective enrichment of malachite green and crystal violet in fish samples, Journal of chromatography. A, 2018, 通讯作者
(22) Strategy for Comprehensive Identification of Acylcarnitines Based on Liquid Chromatography-High-Resolution Mass Spectrometry, ANALYTICAL CHEMISTRY, 2018, 通讯作者
(23) Quality Control of Serum and Plasma by Quantification of (4E,14Z)-Sphingadienine-C18-1- Phosphate Uncovers Common Preanalytical Errors During Handling of Whole Blood, Clinical Chemistry, 2018, 通讯作者
(24) Serum Metabolomics Study of Gliclazide-Modified-Release-Treated Type 2 Diabetes Mellitus Patients Using a Gas Chromatography-Mass Spectrometry Method, JOURNAL OF PROTEOME RESEARCH, 2018, 通讯作者
(25) Inhibition of MAPK pathway is essential for suppressing Rheb-Y35N driven tumor growth, ONCOGENE, 2017, 其他(合作组作者)
(26) MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer, EMBO Reports, 2017, 其他(合作组作者)
(27) Next-generation transgenic cotton: pyramiding RNAi and Bt counters insect resistance, PLANT BIOTECHNOLOGY JOURNAL, 2017, 其他(合作组作者)
(28) Serum Monounsaturated Triacylglycerol Predicts Steatohepatitis in Patients with Non-alcoholic Fatty Liver Disease and Chronic Hepatitis B, SCIENTIFIC REPORTS, 2017, 第 8 作者
(29) Comprehensive Analysis of Short-, Medium-, and Long-Chain AcylCoenzyme A by Online Two-Dimensional Liquid Chromatography/Mass Spectrometry, ANALYTICAL CHEMISTRY, 2017, 通讯作者
(30) High-throughput metabolic profiling based on small amount of hepatic cells, ELECTROPHORESIS, 2017, 第 9 作者
(31) 基于气相色谱质谱联用技术的高通量细胞表型分析方法, 色谱, 2017, 第 5 作者
(32) 智慧型复杂科学仪器数据处理软件系统ChemDataSolution 的开发与应用, 计算机与应用化学, 2017, 通讯作者
(33) 亲水作用色谱/质谱联用方法用于膀胱癌患者血清代谢组学研究, 分析化学, 2017, 第 5 作者
(34) Identification of SPOP related metabolic pathways in prostate cancer, ONCOTARGET, 2017, 通讯作者
(35) Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention, NATURE MEDICINE, 2017, 其他(合作组作者)
(36) Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment, NATURE COMMUNICATIONS, 2017, 第 10 作者
(37) Comprehensive Analysis of Short-, Medium-, and Long-Chain Acyl-Coenzyme A by Online Two-Dimensional Liquid Chromatography/Mass Spectrometry, Analytical chemistry, 2017, 通讯作者
(38) Nontargeted screening of chemical contaminants and illegal additives in food based on liquid chromatography-high resolution mass spectrometry, TRAC-TRENDS IN ANALYTICAL CHEMISTRY, 2017, 通讯作者
(39) Metabolic profiling analysis of Siraitia grosvenorii revealed different characteristics of green fruit and saccharified yellow fruit, JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2017, 通讯作者
(40) An alignment algorithm for LC-MS-based metabolomics dataset assisted by MS/MS information, ANALYTICA CHIMICA ACTA, 2017, 通讯作者
(41) Altered Lipid Metabolism in Recovered SARS Patients Twelve Years after Infection, SCIENTIFIC REPORTS, 2017, 通讯作者
(42) Plasma metabolomics profiling of maintenance hemodialysis based on capillary electrophoresis - time of flight mass spectrometry, SCIENTIFIC REPORTS, 2017, 通讯作者
(43) Simultaneous metabolomics and lipidomics analysis based on novel heart-cutting two-dimensional liquid chromatography-mass spectrometry, ANALYTICA CHIMICA ACTA, 2017, 通讯作者
(44) Discovery and validation of potential urinary biomarkers for bladder cancer diagnosis using a pseudotargeted GC-MS metabolomics method, ONCOTARGET, 2017, 通讯作者
(45) Online Three Dimensional Liquid Chromatography/Mass Spectrometry Method for the Separation of Complex Samples, ANALYTICAL CHEMISTRY, 2017, 通讯作者
(46) Metabolomics Toward Biomarker Discovery, Methods in molecular biology, 2017, 通讯作者
(47) Ultra-high Capacity Liquid Chromatography Chip/Quadrupole Time-of-flight Mass Spectrometry for Pharmaceutical Analysis. , J. Chromatogr. A, 2011, 通讯作者
(48) Liquid chromatography/mass spectrometry-based metabolic profiling to elucidate chemical differences of tobacco leaves between Zimbabwe and China., Journal of Separation Science, 2011, 通讯作者
(49) Method for liver tissue metabolic profiling study and its application in type 2 diabetic rats based on ultra performance liquid chromatography-mass spectrometry., J Chromatogr B Analyt Technol Biomed Life Sci., 2011, 通讯作者
(50) Effect of a Chinese medicine tongxinluo on endothelial dysfunction rats studied by using urinary metabonomics based on liquid chromatography - mass spectrometry., Journal of Pharmaceutical and Biomedical Analysis, 2011, 通讯作者
(51) Metabolomics study of diabetic retinopathy by using gas chromatography mass spectrometry: a comparison of stages and subtypes diagnosed by the Western medicine and Chinese medicine. , Mol. Biosys., 2011, 通讯作者
(52) Application of L-EDA in metabonomics data handling: global metabolite profiling and potential biomarker discovery of epithelial ovarian cancer prognosis. , Metabolomics, 2011, 通讯作者
(53) A method for handling metabonomics data from liquid chromatography/mass spectrometry: combinational use of support vector machine recursive feature elimination, genetic algorithm and random forest for feature selection. , Metabolomics, 2011, 通讯作者
(54) Serum Metabolic Profiling and Features of Papillary Thyroid Carcinoma and Nodular Goiter., Mol. Biosys., 2011, 通讯作者
(55) Serum 27-nor-5β-cholestane-3,7,12,24,25 pentol glucuronide discovered by metabolomics as potential diagnostic biomarker for epithelium ovarian cancer, J. Proteome Res, 2011, 通讯作者
(56) A fully automated system with on-line micro solid-phase extraction combined with capillary liquid chromatography–tandem mass spectrometry for high throughput analysis of microcystins and nodularin-R in tap water and lake water., Journal of Chromatography A, 2011, 通讯作者
(57) Evaluation of ionic liquid stationary phases for one dimensional gas chromatography-mass spectrometry and comprehensive two dimensional gas chromatographic analyses of fatty acids in marine biota. , Journal of Chromatography A, 2011, 通讯作者
(58) Urinary metabonomic study of lung cancer by a fully automatic hyphenated hydrophilic interaction/RPLC-MS system , Journal of Separation Science , 2010, 通讯作者
(59) 中药通心络对抑郁-动脉粥样硬化大鼠干预作用的血浆代谢组学研究 , 中国科学: 化学 , 2010, 通讯作者
(60) Lipidomics Analysis Reveals Efficient Storage of Hepatic Triacylglycerides Enriched in Unsaturated Fatty Acids after One Bout of Exercise in Mice , PLOS ONE , 2010, 通讯作者
(61) 基于HPLC-MS的健康吸烟人群代谢组学研究 , 化学研究与应用 , 2010, 通讯作者
(62) Medium chain acylcarnitines dominate the metabolite pattern in humans under moderate intensity exercise and support lipid oxidation , PLOS ONE , 2010, 通讯作者
(63) Urinary metabonomics study in a rat model in response to protein-energy malnutrition by using gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry , Molecular Biosystems , 2010, 通讯作者
(64) A random forest of combined features in the classification of cut tobacco based on gas chromatography fingerprinting , Talanta , 2010, 通讯作者
(65) Urinary metabolic profiling of colorectal carcinoma based on online affinity solid phase extract-high performance liquid chromatography and ultra performance liquid chromatography-mass spectrometry , Molecular Biosystems , 2010, 通讯作者
(66) 不同石斛枫斗中酚酸类活性成分的比较及杓唇石斛素和石斛酚含量的测定 , 色谱, 2010, 通讯作者
(67) Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry , Molecular BioSystems , 2010, 通讯作者
(68) 卷烟化学指标的因子分析 , 分析科学学报 , 2010, 第 4 作者
(69) 尿中5种修饰核苷用于肺癌高危人群筛查分子标志物的可行性研究, 现代肿瘤医学, 2010, 通讯作者
(70) Effect of traditional Chinese medicine berberine on type 2 diabetes based on comprehensive metabonomics , Talanta, 2010, 通讯作者
(71) Separation and detection of polar cuticular components from Oriental tobacco leaf by integration of normal-phase liquid chromatography fractionation with reversed-phase liquid chromatography-mass spectrometry, Journal of Separation Science , 2010, 第 3 作者
(72) Metabonomic fingerprints of fasting plasma and spot urine reveal human pre-diabetic metabolic traits , Metabolomics, 2010, 通讯作者
(73) Systems Biology-Based Diagnostic Principles as Pillars of the Bridge between Chinese and Western Medicine , Planta Medica , 2010, 通讯作者
发表著作
(1) 气相色谱专家系统, expert system of gas chromatography, 山东科技出版社, 1994-05, 第 2 作者
(2) 分析化学手册(第五分册)气相色谱分析, Analytical Chemistry Handbook( Fifth volumes)gas chromatographic analysis, 化学工业出版社, 1999-03, 第 4 作者
(3) 现代实用气相色谱法, Modern Applied Gas Chromatography Method, 化学工业出版社, 2004-06, 第 1 作者
(4) 色谱进展, Proceedings of Dalian International Symposia and Exhibition on Chromatography, 化学工业出版社, 2007-06, 第 1 作者
(5) 代谢组学——方法与应用, Metabolomics——Methods and Applications, 科学出版社, 2008-08, 第 1 作者
(6) 《分析化学手册:5 气相色谱分析》, Analytical Chemistry Handbook( Fifth volumes)gas chromatographic analysis, 化工出版社, 2016-10, 第 1 作者
科研项目
( 1 ) 复杂生物体系中关键功能代谢物筛选的新方法、新技术研究, 主持, 国家级, 2015-01--2019-12
( 2 ) 代谢性疾病的代谢组学研究, 参与, 国家级, 2007-12--2012-12
( 3 ) 基于系统生物学的中医症候的科学基础研究, 主持, 国家级, 2009-06--2012-05
( 4 ) 基于代谢组学的食品安全检测新方法和新技术研究, 主持, 国家级, 2009-01--2012-12
( 5 ) 应用于临床样本检测的超灵敏、高覆盖代谢组定量分析技术研发, 主持, 国家级, 2017-07--2019-12
( 6 ) 病毒性肝炎相关肝癌代谢紊乱的机制和用药指导研究, 主持, 国家级, 2008-10--2010-12
( 7 ) 转基因生物代谢分子特征识别技术, 主持, 国家级, 2011-01--2015-12
( 8 ) 病毒性肝炎相关肝癌发生发展的代谢特征和个体化用药研究, 主持, 国家级, 2012-01--2015-12
( 9 ) 胶质瘤IDH突变对乙酰辅酶A相关代谢的影响, 主持, 国家级, 2015-01--2018-12
( 10 ) 低丰度重要代谢物的LC-MS分析, 主持, 国家级, 2012-01--2015-12
( 11 ) 卵巢癌临床关键问题导向的诊疗标志物验证及应用研究, 参与, 国家级, 2016-09--2020-12
( 12 ) 转基因生物代谢组水平分子特征分析和鉴定技术研究, 参与, 国家级, 2016-01--2020-12
参与会议
(1)Metabolomics opens a novel window for exploring the biological functions of small molecules 2018-04-10
(2)Capillary Electrophoresis-Mass Spectrometry: A Complementary Technique to Chromatography-Mass Spectrometry for Metabolomics 2017-12-11
(3)LC-MS based metabolomics for personalized medicine 2017-07-02
(4)Metabolomics: From differential metabolite discovery to functional elucidation 2017-06-18
(5)MS-based metabolomics for precision medicine 2017-03-29
(6)Metabolic biomarker discovery and confirmation by using metabonomics Guowang Xu, Jing Chen, Xinjie Zhao, Peiyuan Yin, Xin Lu, Hongwei Kong 2011-06-27
(7)LC-MS based metabolomics for disease biomarker discovery and confirmation 许国旺,赵欣捷,尹沛源,黄强,周丽娜,路鑫 2011-06-19
(8)Applications of comprehensive 2-D gas chromatography/time-of-flight mass spectrometry in plant metabonomics 林晓慧,李勇,路鑫,孔宏伟,许国旺 2010-12-15
(9)LC-MS based metabonomics: separation window extending from either hydrophilic or hydrophobic metabolites to global metabolites 许国旺,石先哲,杨芹,赵素敏,单圆鸿,赵欣捷 2010-12-15
(10)Metabolic biomarker discovery of complicated diseases by using LC-MS based metabonomics 许国旺,陈静,赵欣捷,尹沛源,王文昭,路鑫 2010-09-15
(11)Functional metabolomics-Identification and characterization of biomarkers detected under moderate intensity exercise conditions Lehmann R.,赵欣捷,Weigert C.,Simon P.,Fehrenbach E.,Hoene M.,Schleicher E.D.,Haring H.U.,许国旺,Niess A.M. 2010-06-25
(12)Where and how to fish disease-related metabolite biomarkers by using LC-MS based metabonomics 许国旺,王文昭,尹佩源,黄强,赵新捷,陈世礼,陈静,周丽娜,孔宏伟,路鑫 2010-06-25
(13)LC-MS based Metabonomics: Effect of Preanalytical Procedures 许国旺,尹沛源,赵欣捷,陈世礼,路鑫,E. D. Schleicher, R. Lehmann 2010-06-19
(14)Metabolic Profiling of Liver Tissue Based on UPLC Q-TOF/MS 黄强,许国旺 2010-06-19
(15)Comprehensive identification of metabolic biomarkers in HPLC MSbased 许国旺,赵欣捷,尹沛源,陈静,路鑫 2010-06-16
(16)Analytical Research Alliances – a case study of collaboration between Pfizer and Chinese academic Jian Wang, Gang Xue, Klaus Rumpel, Yining Zhao, Roman Szucs, Pfizer Global Rand D, Pfizer Inc.,顾群, 李钦, 许国旺 2010-04-07
(17)A metabonomics platform based on chromatography-mass spectrometry 许国旺 2010-03-10
(18)Plasma sample preraration in untargeted metabonomics studies by UHPLC/TOF-MS Forcisi S.,Wormann K.,Fekete A.,Lehmann R.,许国旺,Schmitt-Kopplin P. 2010-03-10
(19)UHPLC/TOF-MS method development for untargeted metabolic analysis in urine Wormann K.,Forcisi S.,Fekete A.,Lehmann R.,许国旺,Schmitt-Kopplin P. 2010-03-10
(20)Metabonomics method development based on a new online two-dimensional 许国旺,赵欣捷,陈静,尹沛源,杨芹,路鑫 2010-01-27
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