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庞代文，武汉大学教授，国家杰出青年科学基金获得者(2000年)、首批新世纪百千万人才工程国家级人选（2004年）、湖北省重大人才工程“高端人才引领培养计划”首批人选(第一层次)（2013年）、国家973项目首席科学家、国家纳米科学技术指导协调委员会委员及专家组成员、国家重大科学研究计划（973“纳米研究”专项）专家组成员、国家自然科学基金委创新研究群体学术带头人（“新型生物医学探针技术基础及应用”）、教育部创新团队学术带头人、生物医学分析化学教育部重点实验室主任。 教育与研究经历 武汉大学化学与分子科学学院教授、博导、生物医学分析化学教育部重点实验室主任、法国国家科研中心中法“纳米生物催化电化学国际联合实验室（LIA）”中方共同主任、病毒学国家重点实验室PI，高等研究院高级研究员、国家杰出青年科学基金获得者(2000年)、首批新世纪百千万人才工程国家级人选（2004年）、国家973项目首席科学家（2项：“病毒与细胞相互作用的荧光纳米实时检测新技术及动态过程可视化”和“量子点标记技术研究病毒侵染过程及宿主应答”）、国家自然科学基金委创新研究群体学术带头人（“新型生物医学探针技术基础及应用”）、教育部创新团队学术带头人（“化学生物学应用基础研究”）、国家纳米科学技术指导协调委员会委员、“纳米研究”国家重大科学研究计划（973）专家组成员、“纳米科技”国家重点研发计划实施方案编制专家组成员、国家自然科学基金委化学部专家评审组成员、Analytical Chemistry（美国化学会）顾问编委（2017.1-）、NewJournal of Chemistry（英国皇家化学会）编委（2013.1.-2016.12）和副主编（2017.1-）、Cell & Bioscience（BioMed Central）编委（2010.11-）、Journalof Electroanalytical Chemistry（Elsevier出版社）编委（2005.1-2015.12）、高等学校化学学报副主编（2007.4-）、《分析化学手册》（化学工业出版社）编委、中国化学会分析化学委员会副主任（2002.11-）等。曾任化学与分子科学学院院长（2001.01-2005.02）。从事生物医学分析化学和纳米生物技术研究，已在J. Am. Chem. Soc.、Angew. Chem. Int.Ed.、Adv. Mater.、Chem. Soc. Rev.、ACS Nano、Anal. Chem.、J. Virol.等刊物上发表学术论文250多篇，编著3部，获授权国家发明专利30件，参与制订第1个量子点国家标准。致力于发展量子点标记纳米生物检测与动态示踪/成像新方法，主要是单病毒-活细胞三维实时动态示踪以及肿瘤研究的活体原位实时动态示踪与成像新方法，细菌、病毒、循环肿瘤细胞的快速高灵敏检测新方法等。“活细胞合成量子点等纳米材料”研究成果入选《“十一五”国家重大科技成就展（2011年）》，180多次在国内外作大会特邀报告和特邀专题报告（其中国际学术会议和国际著名大学特邀专题报告73次）。曾获教育部自然科学一等奖(“DNA表面化学及基于DNA的生物传感”，第1完成人，2006年)、宝钢教育奖优秀教师奖（2000年）、全国教育系统先进工作者（2001年）、全国优秀科技工作者（2012年），享受国务院政府特殊津贴（1999年）。2005年3月以其实验室为技术依托创办了“武汉珈源量子点技术开发有限公司”。“量子点新型荧光标记试剂”获“第七届中国国际高新技术成果交易会”“优秀产品奖”。 研究领域与兴趣 生物医学分析化学、纳米生物技术、生物电化学、化学生物学 “DNA表面化学及基于DNA的生物传感”成果获2006年度教育部自然科学奖一等奖（个人排名第一） “活细胞合成量子点等纳米材料”研究成果入选《“十一五”国家重大科技成就展（2011年）》 “量子点新型荧光标记试剂”获“第七届中国国际高新技术成果交易会”“优秀产品奖” 国家杰出青年科学基金获得者(2000年) 首批新世纪百千万人才工程国家级人选（2004年） 国家自然科学基金委创新研究群体学术带头人（2006年） 宝钢教育奖优秀教师奖（2000年） 全国教育系统先进工作者（2001年） 全国优秀科技工作者（2012年） 国务院政府特殊津贴（1999年） [1] Jing-Ya Zhao, GangChen, Yi-Ping Gu, Ran Cui, Zhi-Ling Zhang, Zi-Li Yu, Bo Tang, Yi-FangZhao, Dai-Wen Pang*. Ultrasmall Magnetically Engineered Ag2SeQuantum Dots for Instant Efficient Labeling and Whole-Body High-Resolution MultimodalReal-Time Tracking of Cell-Derived Microvesicles. Journal of theAmerican Chemical Society, 138(2016)1893-1903. DOI:10.1021/jacs.5b10340 [2] Shu-Lin Liu, Zhi-GangWang, Zhi-Ling Zhang, Dai-Wen Pang*. Tracking single virusesinfecting their host cells using quantum dots. Chemical SocietyReviews, 45(2016)1211-1224. DOI:10.1039/C5CS00657K [3] An-An Liu, ZhenfengZhang, En-Ze Sun, Zhenhua Zheng, Zhi-Ling Zhang, Qinxue Hu, HanzhongWang*, Dai-Wen Pang*. Simultaneous Visualization of Parental andProgeny Viruses by a Capsid-Specific HaloTag Labeling Strategy. ACSNano, 10(2016)1147-1155. DOI:10.1021/acsnano.5b06438 [4] Jiao Hu, Zhi-LingZhang, Cong-Ying Wen, Man Tang, Ling-Ling Wu, Cui Liu, Lian Zhu, Dai-WenPang*. Sensitive and Quantitative Detection of C-Reaction Protein Based onImmunofluorescent Nanospheres Coupled with Lateral Flow Test Strip. AnalyticalChemistry, 88(2016)6577-6584. DOI:10.1021/acs.analchem.6b01427 [5] Zhi-Gang Wang, Shu-LinLiu, Yuan-Jun Hu, Zhi-Quan Tian, Bin Hu, Zhi-Ling Zhang, Dai-Wen Pang*.Dissecting the Factors Affecting the Fluorescence Stability of Quantum Dots inLive Cells. ACS Applied Materials & Interfaces,8(13)(2016)8401-8408. DOI: 10.1021/acsami.6b01742 [6] Li Wen, Yi Lin,Zhi-Ling Zhang, Wen Lu, Cheng Lv, Zhi-Liang Chen, Han-Zhong Wang, Dai-WenPang*.Intracellular self-assembly based multi-labeling of key viralcomponents: Envelope, capsid and nucleic acids. Biomaterials,99(2016)24-33. http://dx.doi.org/10.1016/j.biomaterials.2016.04.038 [7] Cheng Lv, Yi Lin,An-An Liu, Zheng-Yuan Hong, Li Wen, Zhenfeng Zhang, Zhi-Ling Zhang, HanzhongWang, Dai-Wen Pang*. Labeling viral envelope lipids with quantumdots by harnessing the biotinylated lipid-self-inserted cellularmembrane. Biomaterials, 106(2016)69-77. http://dx.doi.org/10.1016/j.biomaterials.2016.08.013 [8] Cui Liu, Lei Bao, BoTang, Jing-Ya Zhao, Zhi-Ling Zhang, Ling-Hong Xiong, Jiao Hu, Ling-LingWu, Dai-Wen Pang*. Fluorescence-Converging CarbonNanodots-Hybridized Silica Nanosphere. Small,12(34)(2016)4702-4706. DOI: 10.1002/smll.201503958 [9] Cong-Ying Wen,Hai-Yan Xie, Zhi-Ling Zhang, Ling-Ling Wu, Jiao Hu, Man Tang, Min Wu, Dai-WenPang*. Fluorescent/magnetic micro/nano-spheres based on quantum dots and/ormagnetic nanoparticles: preparation, properties, and their applications incancer studies. Nanoscale, 8(2016)12406-12429. DOI:10.1039/c5nr08534a [10] Lan Chen, Ling-Ling Wu, Zhi-LingZhang, Jiao Hu, Man Tang, Chu-Bo Qi, Na Li, Dai-Wen Pang*.Biofunctionalized magnetic nanospheres-based cell sorting strategy forefficient isolation, detection and subtype analyses of heterogeneouscirculating hepatocellular carcinoma cells. Biosensors andBioelectronics, 85(2016)633-640. http://dx.doi.org/10.1016/j.bios.2016.05.071 [11] Bao-Ping Qi, Lei Bao, Zhi-LingZhang, Dai-Wen Pang*. Electrochemical Methods to StudyPhotoluminescent Carbon Nanodots: Preparation, Photoluminescence Mechanism andSensing. ACS Applied Materials & Interfaces,8(2016)28372-28382. DOI: 10.1021/acsami.5b11551. Publication Date (Web): February 24, 2016 [12] Xiao-Jing Xing, Wan-Lu Xiao, Xue-GuoLiu, Ying Zhou, Dai-Wen Pang, Hong-Wu Tang*. A fluorescentaptasensor using double-stranded DNA/graphene oxide as the indicatorprobe. Biosensors & Bioelectronics, 78(2016)431-437. 10.1016/j.bios.2015.11.076 [13] Xiaojing Xing, Xueguo Liu, Ying Zhou,Dangdang Xu, Dai-Wen Pang, Hongwu Tang*. Graphene oxide enhancedspecificity at aptamer and its application to multiplexed enzymatic activitysensing. RSC Advances, 6(14)(2016)11815-11821. 10.1039/c5ra25481g [14] Feng Tang, Dai-Wen Pang,Zhi Chen, Jian-Bo Shao, Ling-Hong Xiong, Yan-Ping Xiang, Yan Xiong, Kai Wu,Hong-Wu Ai, Hui Zhang, Xiao-Li Zheng, Jing-Rui Lv, Wei-Yong Liu, Hong-Bing Hu,Hong Mei, Zhen Zhang, Hong Sun, Yun Xiang, Zi-Yong Sun*. Visual and efficientimmunosensor technique for advancing biomedical applications of quantum dots onSalmonella detection and isolation. Nanoscale,8(8)(2016)4688-4698. 10.1039/c5nr07424j 2016 [15] Man Tang, Cong-Ying Wen, Ling-Ling Wu,Shao-Li Hong, Jiao Hu, Chun-Miao Xu, Dai-Wen Pang, Zhi-Ling Zhang*.A chip assisted immunomagnetic separation system for the efficient capture andin situ identification of circulating tumor cells. Lab on a Chip,16(7)(2016)1214-1223. 10.1039/c5lc01555c 2016 [16] Changliang Zhang, Jia-Quan Xu, Yu-TaoLi, Le Huang, Dai-Wen Pang, Yong Ning, Wei-Hua Huang, ZhiyongZhang, Guo-Jun Zhang*. Photocatalysis-Induced Renewable Field-Effect Transistorfor Protein Detection. Analytical Chemistry, 88(7)(2016)4048-4054. 10.1021/acs.analchem.6b00374 [17] Cheng-Yu Li, Di Cao, Ya-Feng Kang, YiLin, Ran Cui, Dai-Wen Pang, Hong-Wu Tang*. Fluorescence Detectionof H5N1 Virus Gene Sequences Based on Optical Tweezers with Two-PhotonExcitation Using a Single Near Infrared Nanosecond Pulse Laser. AnalyticalChemistry, 88 (8)(2016)4432-4439. 10.1021/acs.analchem.6b00065 [18] Li-Juan Shi, Chun-Nan Zhu, He He,Dong-Liang Zhu, Zhi-Ling Zhang, Dai-Wen Pang, Zhi-Quan Tian*.Near-infrared Ag2Se quantum dots with distinct absorption features and highfluorescence quantum yields. RSC Advances,6(44)(2016)38183-38186. 10.1039/c6ra04987g [19] Ling-Hong Xiong, Ran Cui, Hui-Hui Liu,Yong Li, Zhi-Xiong Xie, Zhi-Ling Zhang, Bin Hu, Dai-Wen Pang*. Livecell synthesis of inorganic nanomaterials. Sci Sin Chem,46(2016)163-172. doi: 10.1360/N032015-00165 [20] Yu-DanYe, Li Xia, Dang-Dang Xu,Xiao-Jing Xing, Dai-Wen Pang, Hong-Wu Tang*. DNA-stabilized silvernanoclusters and carbon nanoparticles oxide: A sensitive platform for label-freefluorescence turn-on detection of HIV-DNA sequences. Biosensors& Bioelectronics, 85(2016)837-843. 10.1016/j.bios.2016.06.001 [21] Jia-Kai Wu, Zhi-Quan Tian, Zhi-LingZhang, An-An Liu, Bo Tang, Li-Juan Zhang, Zhi-Liang Chen, Dai-Wen Pang*.Purification of quantum dot-based bioprobes via high-performance size exclusionchromatography. Talanta, 159(2016)64-73. 10.1016/j.talanta.2016.05.078 [22] Zhen Wu, Chuan-Hua Zhou, Liang-JunPan, Tao Zeng, Lian Zhu, Dai-Wen Pang, Zhi-Ling Zhang*. ReliableDigital Single Molecule Electrochemistry for Ultrasensitive AlkalinePhosphatase Detection. Analytical Chemistry,88(18)(2016)9166-9172. 10.1021/acs.analchem.6b02284 [23] Di Cao, Cheng-Yu Li, Ya-Feng Kang, YiLin, Ran Cui, Dai-Wen Pang, Hong-Wu Tang*. Dual-component genedetection for H7N9 virus - The combination of optical trapping and bead-basedfluorescence assay. Biosensors & Bioelectronics,86(2016)1031-1037; 10.1016/j.bios.2016.07.040 [24] Lei Bao, Cui Liu, Zhi-LingZhang, Dai-Wen Pang*. Photoluminescence-Tunable Carbon Nanodots:Surface-State Energy-Gap Tuning. Advanced Materials,27(2015)1663-1667.DOI: 10.1002/adma.201405070 [25] Gang Chen, Jun-Yi Zhu, Zhi-Ling Zhang,Wei Zhang, Jian-Gang Ren, Min Wu, Zheng-Yuan Hong, Cheng Lv, Dai-WenPang*, Yi-Fang Zhao*. Transformation of Cell-Derived Microparticles intoQuantum-Dot-Labeled Nanovectors for Antitumor siRNA Delivery. AngewandteChemie-International Edition, 54(2015)1036-1040. DOI:10.1002/anie.201410223 [26] Zheng-Yuan Hong, Cheng Lv, An-An Liu,Shu-Lin Liu, En-Ze Sun, Zhi-Ling Zhang, Ai-Wen Lei, Dai-Wen Pang*.Clicking Hydrazine and Aldehyde: The Way to Labeling of Viruses with QuantumDots. ACS Nano, 9(12)(2015)11750-11760. DOI:10.1021/acsnano.5b03256 [27] Jia-Jia Wang, Yong-Zhong Jiang, YiLin, Li Wen, Cheng Lv, Zhi-Ling Zhang, Gang Chen, Dai-Wen Pang*.Simultaneous Point-of-Care Detection of Enterovirus 71 and CoxsackievirusB3. Analytical Chemistry, 87(21)( 2015)11105-11112. DOI: 10.1021/acs.analchem.5b03247 [28] Min Wu, Zhi-Ling Zhang, Gang Chen,Cong-Ying Wen, Ling-Ling Wu, Jiao Hu, Chao-Chao Xiong , Jian-Jun Chen*, Dai-WenPang*. Rapid and Quantitative Detection of Avian Influenza A(H7N9) Virionsin Complex Matrices Based on Combined Magnetic Capture and Quantum Dot Labeling. Small,11(No. 39)(2015)5280-5288. DOI: 10.1002/smll.201403746 [29] Ling-Hong Xiong, Ran Cui, Zhi-LingZhang, Jia-Wei Tu, Yun-Bo Shi, Dai-Wen Pang*. HarnessingIntracellular Biochemical Pathways for In Vitro Synthesis of Designer TelluriumNanorods. Small, 11(No. 40)(2015)5416-5422. DOI:10.1002/smll.201500816 [30] Peng Jiang, Dong-Liang Zhu, Chun-NanZhu, Zhi-Ling Zhang, Guo-Jun Zhang, Dai-Wen Pang*. A highlyreactive chalcogenide precursor for the synthesis of metal chalcogenide quantumdots. Nanoscale, 7(2015)19310-19316. DOI: 10.1039/c5nr05747g [31] Bao-Ping Qi, Hui Hu, Lei Bao, Zhi-LingZhang, Bo Tang, Ying Peng, Bao-Shan Wang, Dai-Wen Pang*. Anefficient Edge-Functionalization Method to Tune the Photoluminescence ofGraphene Quantum Dots. Nanoscale, 7(2015)5969-5973. DOI:10.1039/c5nr00842e [32] Peng Jiang, Chun-Nan Zhu, Dong-LiangZhu, Zhi-Ling Zhang, Guo-Jun Zhang, Dai-Wen Pang*. Aroom-temperature method for coating a ZnS shell on semiconductor quantumdots. Journal of Materials Chemistry C, 3(2015)964-967. DOI:10.1039/c4tc02437k [33] Ze-Zhong Chen, Li Cai, Min-Yan Chen,Yi Lin, Dai-Wen Pang, Hong-Wu Tang*. Indirect immunofluorescencedetection of E. coli O157:H7 with fluorescent silica nanoparticles.Biosensors& Bioelectronics, 66(2015)95-102. DOI: 10.1016/j.bios.2014.11.007 [34] Ying Zhou, Xiao-Jing Xing, Dai-WenPang, Hong-Wu Tang*. An exonuclease III-aided "turn-on"fluorescence assay for mercury ions based on graphene oxide and metal-mediated"molecular beacon". RSC Advances,5(17)(2015)12994-12999. DOI: 10.1039/c4ra14024a [35] Fen Cheng, Yue He, Xiao-Jing Xing,Dai-Di Tan, Yi Lin, Dai-Wen Pang, Hong-Wu Tang*. A goldnanoparticle-based label free colorimetric aptasensor for adenosine deaminasedetection and inhibition assay. Analyst,140(5)(2015)1572-1577. 10.1039/c4an02070g [36] Zhen Wu, Chuan-Hua Zhou, Jian-JunChen*, Chaochao Xiong, Ze Chen, Dai-Wen Pang, Zhi-LingZhang*. Bifunctional magnetic nanobeads for sensitive detection of avianinfluenza A (H7N9) virus based on immunomagnetic separation and enzyme-inducedmetallization. Biosensors & Bioelectronics,68(2015)586-592. 10.1016/j.bios.2015.01.051 [37] Hao Xu, Chuang Chen, Yue He, Hong-WuTang*, Zhi-Ling Zhang, Yan Li, Dai-Wen Pang. Analysis of CancerMarker in Tissues with Hadamard Transform Fluorescence Spectral MicroscopicImaging. Journal of Fluorescence, 25(2)(2015)397-402. 10.1007/s10895-015-1525-1 [38] Jing Ping Yuan, Lin Wei Wang, Ai PingQu, Jia Mei Chen, Qing Ming Xiang, Chuang Chen, Sheng-Rong Sun, Dai-WenPang, Juan Liu, Yan Li*. Quantum Dots-Based Quantitative and In SituMultiple Imaging on Ki67 and Cytokeratin to Improve Ki67 Assessment in BreastCancer. Plos One, 10(4)(2015)10.1371/journal.pone.0122734 [39] Chuan-Hua Zhou, Zhen Wu, Jian-JunChen, Chaochao Xiong, Ze Chen, Dai-Wen Pang, Zhi-Ling Zhang*.Biometallization-Based Electrochemical Magnetoimmunosensing Strategy for AvianInfluenza A (H7N9) Virus Particle Detection. CHEMISTRY-AN ASIANJOURNAL, 10(6)(2015)1387-1393. 10.1002/asia.201500105 [40] Xiao-Ling Liu, Ji-Ying Hu, Meng-YunHu, Yi Zhang, Zheng-Yuan Hong, Xiao-Qing Cheng, Jie Chen, Dai-Wen Pang,Yi Liang*. Sequence-dependent abnormal aggregation of human Tau fragment in aninducible cell model. Biochimica et Biophysica Acta-MolecularBasis of Disease, 1852(8)(2015)1561-1573. 10.1016/j.bbadis.2015.04.015 [41] Yun Shu, Peng Jiang, Dai-WenPang, Zhi-Ling Zhang*. Droplet-based microreactor for synthesis ofwater-soluble Ag2S quantum dots. Nanotechnology,26(27)(2015):10.1088/0957-4484/26/27/275701 [42] Feng-Min Shen, Lian Zhu, Heng Ye,Yu-Jun Yang, Dai-Wen Pang, Zhi-Ling Zhang*. A High ThroughputMicro-Chamber Array Device for Single Cell Clonal Cultivation and TumorHeterogeneity Analysis. Scientific Reports, 5(2015):10.1038/srep11937 [43] Pei-Lin Guo. Man Tang, Shao-Li Hong,Xu Yu, Dai-Wen Pang, Zhi-Ling Zhang*. Combination of dynamicmagnetophoretic separation and stationary magnetic trap for highly sensitiveand selective detection of Salmonella typhimurium in complex matrix. Biosensors& Bioelectronics, 74(2015)628-636. 10.1016/j.bios.2015.07.019 [44] Cong-Ying Wen, Ling-Ling Wu, Zhi-LingZhang, Yu-Lin Liu, Shao-Zhong Wei, Jiao Hu, Man Tang, En-Ze Sun, Yi-Ping Gong,Jing Yu, Dai-Wen Pang*. Quick-Response Magnetic Nanospheres forRapid, Efficient Capture and Sensitive Detection of Circulating TumorCells. ACS Nano, 8(1)(2014)941-949. DOI:10.1021/nn405744f [45] Ling-Hong Xiong, Ran Cui, Zhi-LingZhang, Xu Yu, Zhixiong Xie, Yun-Bo Shi, Dai-Wen Pang*. UniformFluorescent Nanobioprobes for Pathogen Detection. ACS Nano,8(5)(2014)5116-5124. DOI: 10.1021/nn501174g (Highlighted byJing Shang and Xiaohu Gao*: A living light bulb, ultrasensitive biodetectionmade easy. Cell & Bioscience 2014 4:34) [46] Li Wen, Yi Lin, Zhen-Hua Zheng,Zhi-Ling Zhang, Li-Juan Zhang, Li-Ying Wang, Han-Zhong Wang, Dai-Wen Pang*.Labeling the nucleocapsid of enveloped baculovirus with quantum dots forsingle-virus tracking. Biomaterials, 35(2014)2295-2301. 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[51] Yan-Min Long, Lei Bao, Jing-Ya Zhao,Zhi-Ling Zhang, Dai-Wen Pang*. Revealing Carbon Nanodots AsCoreactants of the Anodic Electrochemiluminescence of Ru(bpy)32+.AnalyticalChemistry, 86(2014)7224-7228. dx.doi.org/10.1021/ac502405p [52] Jun Hu, Cong-Ying Wen, Zhi-Ling Zhang,Min Xie, Hai-Yan Xie, Dai-Wen Pang*. Recognition Kinetics ofBiomolecules at the Surface of Different-Sized Spheres. BiophysicalJournal, 107(2014)165-173. [53] Jing-Ya Zhao, Ran Cui, Zhi-Ling Zhang,Mingxi Zhang, Zhi-Xiong Xie, Dai-Wen Pang*. Cytotoxicity ofnucleus-targeting fluorescent gold nanoclusters. Nanoscale,6(2014)13126–13134. [54] Qing-Ying Luo, Yi Lin, Jun Peng,Shu-Lin Liu, Zhi-Ling Zhang, Zhi-Quan Tian, Dai-Wen Pang*.Evaluation of nonspecific interactions between quantum dots and proteins.PhysicalChemistry Chemical Physics, 16(2014)7677-7680. [55] Chuan-Hua Zhou, Jing-Ya Zhao, Dai-WenPang, Zhi-Ling Zhang*. 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发表于 2018-3-27 20:09:06
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