|
邱丽萍,湖南大学化学化工学院教授,博士生导师。2014年博士毕业于湖南大学,毕业后留校任教;2012-2014年赴美国佛罗里达大学进行交流学习;2016年赴荷兰拉德堡德大学医学研究中心开展博士后研究;2017年以洪堡学者身份赴德国联邦材料开发与测试研究所进行深造。主要致力于分析化学与生物医学交叉领域研究,围绕细胞生物分子事件研究面临的挑战性问题,以功能核酸为基本分子工具,针对性地进行分子识别与传感探针的设计,取得了阶段性研究进展:发展微环境激活的探针设计策略,提高了功能核酸对病变体系分子识别的特异性;发展亚细胞定位的探针设计策略,为细胞局域分子事件的实时成像提供了新技术;发展原位光响应的探针设计策略,为蛋白的亚细胞定位及活性调控研究提供了新思路。
邱丽萍,教授,洪堡学者
研究方向:化学生物传感、生物纳米技术、肿瘤免疫
2014年于湖南大学获分析化学博士学位,毕业后留校任教。2012-2014年,赴美国佛罗里达大学进行交流学习。2015-2016年赴荷兰奈梅亨大学医学研究中心进行博士后研究。2017年,以洪堡学者身份赴德国联邦材料测试与开发研究所进行深造。入选中国科协2016-2018年度“青年人才托举工程”。目前已在Cell Chem, J. Am. Chem. Soc., Nano Letter.等杂志上发表了30多篇论文。
Research Interest: Chemo/Biosensing, Bionanotechnology, Tumor Immunology
Dr. Liping Qiu earned her Ph.D. in Analytical chemistry at Hunan University in 2014, and worked there as assistant professor after graduation. Within her Ph.D education, she spent two years, as a visiting student, at University of Florida, the USA, From 2015 to 2016, she worked as a postdoc at the Tumor Immunology department of Radboud University Medical Center, the Netherlands. In 2017, she was selected as an Alexander von Humboldt Fellow and worked at Bundesanstalt für Materialforschung und -prüfung, Germany. She has published over 30 scholarly papers in internationally journals including Cell Chem, J. Am. Chem. Soc., Nano Letter, etc
Selected Publications:
1. Sitao Xie, Liping Qiu*, Liang Cui, Honglin Liu, Hao Liang, Ding Ding, Lei He, Huixia Liu, Zhou Chen, Xiaobing Zhang and Weihong Tan*, Reversible and Quantitative Photoregulation of Target Proteins. Chem, 2017, 3, 1021–1035
2. Liping Qiu, Florian Wimmers, Jorieke Weiden, Hans A. Heus, Jurjen Tel* and Carl G. Figdor*, A membrane-anchored aptamer sensor for probing IFNc secretion by single cells. Chem. Commun., 2017, 53, 8066-8069
3. Liqin Zhang, Shuo Wan, Ying Jiang, Yanyue Wang, Ting Fu, Qiaoling Liu, Zhijuan Cao, Liping Qiu* and Weihong Tan*, Molecular Elucidation of Disease Biomarkers at the Interface of Chemistry and Biology. J. Am. Chem. Soc. 2017, 139, 2532−2540
4. Liping Qiu, Tao Chen, Ismail öçsoy, Emir Yasun, Cuichen Wu, Guizhi Zhu, Mingxu You, Da Han, Jianhui Jiang, Ruqin Yu and Weihong Tan*, A Cell-Targeted, Size-Photocontrollable, Nuclear-Uptake Nanodrug Delivery System for Drug-Resistant Cancer Therapy. Nano Letters, 2015, 15 (1), 457–463
5. Liping Qiu, Tao Zhang, Jianhui Jiang*, Cuichen Wu, Guizhi Zhu, Mingxu You, Xigao Chen, Liqin Zhang, Cheng Cui, Ruqin Yu and Weihong Tan*, Cell Membrane-Anchored Biosensors for Real-Time Monitoring of the Cellular Microenvironment. J. Am. Chem. Soc. 2014, 136 (38), 13090–13093
教育背景
2012–2014,联合培养博士,美国佛罗里达大学
2009–2014,博士,湖南大学
2005–2009,本科,湖南大学
工作履历
2018.1-至今,副教授,湖南大学化学化工学院
2017.11-2018.2,洪堡学者,德国联邦理工材料研究与测试中心
2014.12-2017.12,助理教授,湖南大学化学化工学院
2015.12-2016.12,博士后,荷兰奈梅亨大学医学研究中心肿瘤免疫系
研究领域
化学生物传感、生物纳米技术、肿瘤免疫
科研项目
1. 国家自然科学基金重大研究计划培育项目,91753109,基于核酸适配体的RNA动态化学修饰研究新方法,2018/01-2020/12,70万,在研,主持
2. 中国科协“青年人才托举工程”,2016QNRC001,基于功能核酸的单免疫细胞分析,2016/01-2018/12,45万,在研,主持
3. 国家自然科学基金青年科学基金项目,21505039,细胞膜定位功能核酸探针的构建及其在细胞外微环境荧光成像应用的研究,2016/01-2018/12,25.2万,在研,主持
4. 国家重点实验室优秀青年教师项目, 基于核酸适配体的细胞信号传递机制研究, 2017.1-2017.12,30万,结题,主持
学术成果
1. Sitao Xie, Liping Qiu*, Liang Cui, Honglin Liu, Hao Liang, Ding Ding, Lei He, Huixia Liu, Zhou Chen, Xiaobing Zhang and Weihong Tan*, Reversible and Quantitative Photoregulation of Target Proteins. Cell Chem, 2017, 3, 1021–1035
2. Liqin Zhang, Shuo Wan, Ying Jiang, Yanyue Wang, Ting Fu, Qiaoling Liu, Zhijuan Cao, Liping Qiu* and Weihong Tan*, Molecular Elucidation of Disease Biomarkers at the Interface of Chemistry and Biology. J. Am. Chem. Soc. 2017, 139, 2532−2540
3. Liping Qiu, Tao Chen, Ismail öçsoy, Emir Yasun, Cuichen Wu, Guizhi Zhu, Mingxu You, Da Han, Jianhui Jiang, Ruqin Yu and Weihong Tan*, A Cell-Targeted, Size-Photocontrollable, Nuclear-Uptake Nanodrug Delivery System for Drug-Resistant Cancer Therapy. Nano Letters, 2015, 15 (1), 457–463
4. Liping Qiu, Tao Zhang, Jianhui Jiang*, Cuichen Wu, Guizhi Zhu, Mingxu You, Xigao Chen, Liqin Zhang, Cheng Cui, Ruqin Yu and Weihong Tan*, Cell Membrane-Anchored Biosensors for Real-Time Monitoring of the Cellular Microenvironment. J. Am. Chem. Soc. 2014, 136 (38), 13090–13093
5. Liping Qiu, Cuichen Wu, Mingxu You, Da Han, Tao Chen, Guizhi Zhu, Jianhui Jiang, Ruqin Yu and Weihong Tan, A Targeted, Self-delivered and Photocontrolled Molecular Beacon for Spatiotemporal mRNA Detection in Living Cells. J. Am. Chem. Soc. 2013, 135 (35), 12952 − 12955
|
声明:本网部分文章和图片来源于网络,发布的文章仅用于材料专业知识和市场资讯的交流与分享,不用于任何商业目的。任何个人或组织若对文章版权或其内容的真实性、准确性存有疑义,请第一时间联系我们,我们将及时进行处理。
|