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徐勇前,博士,西北农林科技大学化学与药学院教授,博士生导师。2006年大连理工大学应用化学专业博士毕业,师从精细化工国家重点实验室主任彭孝军院士。2008-2011年美国阿克伦大学博士后。现任教育部学位中心通讯评议专家,Chemical Science,Biomacromolecules, Biosensors and Bioelectronics, Analyst,Dalton Transactions, RSC Advances, New Journal of Chemistry等国际学术期刊审稿人。2015年获全国大学生科创项目“优秀指导老师”称号。至今共主持国家自然科学基金项目3项,省科技攻关项目1项。研究方向为化学生物分析,利用荧光分析手段来标记、跟踪、检测生物分子、药物分子及有害物质,为食品安全、环境检测、疾病诊断及药物释放等方面提供信息。2011年至今以第一作者或通讯作者发表论文30篇,其中中科院一区论文19篇。
一、个人简介
徐勇前,博士,西北农林科技大学化学与药学院副教授,博士生导师。 2006年12月博士毕业于大连理工大学应用化学专业。2008年~2011年,美国阿克伦大学有机化学系博士后。
二、科研课题
1. 国家自然科学基金面上项目,肝细胞线粒体内双活性氧多通道探针研究,21676218,2017.01-2020.12
2. 国家自然科学基金面上项目,近红外菁染料聚集调控及其用于生物分子检测研究,21476185,2015.01-2018.12
3. 国家自然科学基金青年项目,可用于诊断与治疗一体化的新型纳米高分子聚合物“点”的构建,21206137,2013.01-2015.12
4. 陕西省社会发展科技攻关项目,功能纳米材料用于恶性肿瘤的诊疗,2014K11-01-02-06,2014.01-2015.12
三、研究领域
研究领域涉及金属配合物和荧光染料电荷电子转移的调控研究,以及生物分子及离子荧光传感器方向的研究。
研究方向:化学生物分析,主要利用荧光分析手段来标记、跟踪、检测生物分子、药物分子及有害物质,为食品安全、环境检测、疾病诊断及药物释放等方面提供信息,包括:
1、近红外荧光染料分子、功能荧光纳米粒子设计、合成及其在小分子、生物大分子方面的检测应用;
2、功能材料单分子层石墨及碳纳米管纯化及其在生物检测中的应用;
3、主-客分子荧光自组装分子材料的研究及其在分析科学领域应用。
四、开设课程
承担本科生《分析化学》和《分析化学实验》课程的教学工作。
五、主要科研成果与学术论文
Dejia Wang, Hongwei Zhao, Hongjuan Li, Shiguo Sun and Yongqian Xu*, A fluorescent ‘‘glue’’ of water triggered by hydrogen-bonding cross-linking, J. Mater. Chem. C , 2016, 4 , 11050-11054. (Front cover)
Ruizhi Feng, Yongqian Xu*, Hongwei Zhao, Xuemei Duan and Shiguo Sun, A novel platform self-assembled from squaraineembedded Zn(II) complexes for selective monitoring of ATP and its level fluctuation in mitotic cells, Analyst , 2016, 141 , 3219-3223.
Xiaopeng Fan, Qingyuan He, Shiguo Sun, Hongjuan Li, Yuxin Pei and Yongqian Xu*, Nanoparticles self-assembled from multiple interactions: a novel near-infrared fluorescent sensor for detection of serum albumin in human sera and turn-on live-cell imaging, Chem. Commun ., 2016, 52, 1178-1181.
Jia Tu, Shiguo Sun and Yongqian Xu*, A novel self-assembled platform for ratiometric fluorescent detection of spermine , Chem. Commun. , 2016, 52, 1040-1043.
Dan Zhang, Zihao Yang, Hongjuan Li, Zhichao Pei, Shiguo Sun and Yongqian Xu*, A simple excited-state intramolecular proton transfer probe based on a new strategy of thiol-azide reaction for the selective sensing of cysteine and glutathione, Chem. Commun. , 2016, 52, 749-752.
Benhao Li, Weiwei Li, Yongqian Xu,* Jiang Li, Jia Tu and Shiguo Sun, A simple approach for the discrimination of surfactants based on the control of squaraines aggregation, Chem. Commun. , 2015, 51 , 14652-14655.
Qingyuan He, Xiaopeng Fan, Shiguo Sun, Hongjuan Li, Yuxin Pei and Yongqian Xu*, Highly selective turn-on detection of (strept)avidin based on self-assembled near-infrared fluorescent probes, RSC Adv. , 2015, 5 , 38571-38576.
Jia Tu, Liangliang Xiao, Yingfang Jiang, Qingyuan He, Shiguo Sun, Yongqian Xu*, Near-infrared fluorescent turn-on detection of paraquat using an assembly of squaraine and surfactants, Sensors Actuat. B-Chem. , 2015, 215 , 382-387.
Liangliang Xiao, Shiguo Sun, Zhichao Pei, Yuxin Pei, Yi Pang and Yongqian Xu*, A Ga3+ self-assembled fluorescent probe for ATP imaging in vivo, Biosens. Bioelectron. , 2015, 65 , 166-170.
Liangliang Xiao, Jia Tu, Shiguo Sun*, Zhichao Pei, Yuxin Pei, Yi Pang and Yongqian Xu*, A fluorescent probe for hydrazine and its in vivo applications, RSC Adv. , 2014, 4 (79), 41807-41811.
Yongqian Xu*, Benhao Li, Liangliang Xiao, Jia Ouyang, Shiguo Sun* and Yi Pang, A colorimetric and near-infrared fluorescent probe with high sensitivity and selectivity for acid phosphatase and inhibitor screening, Chem. Commun. , 2014, 50 (63), 8677-8680.
Yongqian Xu*, Liangliang Xiao, Shiguo Sun*, Zhichao Pei, Yuxin Pei, Yi Pang, Switchable and selective detection of Zn2+ or Cd2+ in living cells based on 3′- O -substituted arrangement of benzoxazole-derived fluorescent probes, Chem. Commun. , 2014, 50 , 7514-7516.
Yongqian Xu*, Dan Zhang, Benhao Li, Yunfei Zhang, Shiguo Sun, Yi Pang, A near infrared fluorescent dye for trivalent ions sensing and working as a molecular keypad lock, RSC Adv. , 2014, 4 (23), 11634-11639.
Yongqian Xu*, Liangliang Xiao, Yunfei Zhang, Shiguo Sun, Yi Pang, Substituent effect on fluorophores instead of ionophores: its implication in highly selective fluorescent probe for Zn2+ over Cd2+, RSC Adv. , 2014, 4 (10), 4827-4830.
Yongqian Xu*, Benhao Li, Liangliang Xiao, Weiwei Li, Chenyuan Zhang, Shiguo Sun* and Yi Pang, The sphere-to-rod transition of squaraine-embedded micelles: a self-assembly platform displays a distinct response to cysteine and homocysteine, Chem. Commun. , 2013, 49(70) , 7732-7734.
Yongqian Xu*, Benhao Li, Weiwei Li, Jie Zhao, Shiguo Sun*, Yi Pang, ‘‘ICT-not-quenching’’ near infrared ratiometric fluorescent detection of picric acid in aqueous media, Chem. Commun. , 2013, 49(42), 4764-4766.
Yongqian Xu*, Benhao Li, Pan Han, Shiguo Sun*, Yi Pang*, Near-infrared fluorescent detection of glutathione via reaction-promoted assembly of squaraine-analyte adducts, Analyst , 2013, 138(4) , 1004-1007.
六、联系方式
通讯地址:西北农林科技大学化学与药学院
邮编:712100
邮箱:xuyq@nwsuaf.edu.cn
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