广西师范大学化学与药学学院无机化学陈振锋

huyou

陈振锋
联系方式
办公电话：(0773)2120998
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基本介绍
博士，1969年11月生于广西北流市。2001年6月毕业于南京大学无机化学专业，获理学博士学位。2001年晋升副教授，2003年被破格晋升教授。2004年被评为广西新世纪“百千万人才工程”第二层次人选，教育部“新世纪优秀人才支持计划”人选。2006-2007到加拿大University of British Columbia化学系Chris Orvig教授实验室作访问研究。2011年被聘为广西首批“八桂学者”（药物化学）。现任化学与药学学院副院长、药用资源化学与药物分子工程教育部重点实验室常务副主任，广西药用资源化学与药物分子工程实验室----省部共建国家重点实验室培育基地常务副主任。主要承担本科生《无机化学》和研究生的《现代配位化学》等课程的教学工作。作为硕士生导师，已指导或合作硕士研究生40多名，独立或合作指导博士研究生8名。先后主持973计划前期研究专项1项，国家自然科学基金项目3项，教育部”创新团队发展计划”项目1项，教育部重点项目2项，教育部“新世纪优秀人才支持计划”资助项目1项，广西自然科学基金项目4项。作为第二成员参与国家自然科学基金地区基金联合资助项目1项，973计划前期研究专项各3项。近年来已在《Chem. Eur. J.》，《Chem. Commun.》，《Analytical Chemistry》, 《Inorg. Chem.》,《Organometallics》,《CrystEngComm》,《Dalton Trans.》,《J. Biol. Inorg. Chem.》，《J. Inorg. Biochem.》，《Eur. J. Med. Chem.》《Bioorg. & Med. Chem. Lett.》，《Anti-Cancer Agents in Medicinal Chemistry》《Eur. J. Inorg. Chem.》等国际、国内刊物正式发表SCI收录论文120余篇，他人引用1100余次。作为第一完成人2012年获广西自然科学奖三等奖1项,作为第二完成人2003年获广西科技进步一等奖1项。现任广西自然科学基金委员会常务委员，《广西师范大学学报》编委和《Crystal & Growth Design》，《CrystEngComm》,《Dalton Trans.》，《Evidence Based Complementary and Alternative Medicine》，《Mini-Reviews in Medicinal Chemistry》，《Eur. J. Med. Chem.》《Bioorg. & Med. Chem. Lett.》，《Inorganic Chemistry Communications》，《Inorg. Chim. Acta》,《Appl. Organometal. Chem.》,《J. Coord. Chem.》，《中国科学》，《化学学报》,《结构化学》，《有机化学》等近20种刊物的审稿人。
研究方向
基于中药活性成分金属抗肿瘤药物、抗糖尿病药物的研究。
论著专利
1．Pei Liu, Heng-shan Wang, Ying-ming Pan,* Wei-long Dai, Hong Liang and Zhen-Feng Chen*. The first palladium-catalyzed 1,4-addition of terminal alkenes to acrylate esters. Chem. Commoun., 2013, 49, 5295-5297.
2. Yan-Cheng Liu, Zhen-Feng Chen*, Xiao-Yan Song, Yan Peng, Qi-Pin Qin, Hong Liang*. Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dibromo-8-quinolinolato- lanthanides. European Journal of Medicinal Chemistry, 2013, 59, 168-175.
3. Zhen-Feng Chen*, Yun-Qiong Gu, Xiao-Yan Song, Yan-Cheng Liu, Yan Peng, Hong Liang*. Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dichloro-8- quinolinolato-lanthanides. European Journal of Medicinal Chemistry, 2013, 59, 194-202.
4. Zhen-Feng Chen*, Yan Peng, Yun-Qiong Gu, Yan-Cheng Liu, Mei Liu, Ke-Bin Huang, Kun Hu and Hong Liang*. High antitumor activity of 5,7-dihalo-8- quinolinolato tin(IV) complexes. European Journal of Medicinal Chemistry, 2013, 2013, 62,51-58.
5. Ke-Bin Huang, Zhen-Feng Chen*, Yan-Cheng Liu, Zhu-Quan Li, Jian-Hua Wei, Meng Wang， Guo-Hai Zhang, Hong Liang*. Platinum(II) complexes with mono-aminopho- sphonate ester targeting group that induce apoptosis through G1 cell-cycle arrest: Synthesis, crystal structure and antitumour activity. European Journal of Medicinal Chemistry, 2013, 63, 76-84.
6. Ke-Bin Huang, Zhen-Feng Chen,* Yan-Cheng Liu, Zhu-Quan Li, Jian-Hua Wei, Meng Wang, Xiao-Li Xie, and Hong Liang*. Platinum(II) complexes containing aminophosphonate esters: synthsis, characterization, cytotoxicity and action mechanism. European Journal of Medicinal Chemistry, 2013, 64,554-561.
7. Yan Peng, Min-Min Zhang, Zhen-Feng Chen,* Kun Hu, Yan-Cheng Liu, Xia Chen and Hong Liang*. Synthesis, characterization and interaction with biomolecules of platinum(II) complexes with shikimic acid-based ligands. Bioinorganic Chemistry and Applications, Volume 2013, Article ID 565032, 12 pages.
8．Zhen-Feng Chen*, Yan-Fang Shi, Yan-Cheng Liu, Xue Hong, Bo Geng, Yan Peng, Hong Liang*, TCM active ingredient oxoglaucine metal complexes: Crystal structure, cytotoxicity and interaction with DNA. Inorganic Chemistry, 2012, 51, 1998-2009.
9．Huang Tang, Hai-Tao Zhao, Shu-Ming Zhong, Zhi-Yu Wang, Zhen-Fen Chen*, Hong Liang*, Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Bioorganic & Medicinal Chemistry Letters, 2012, 22, 2257-2261.
10．Zhen-Feng Chen*, Yan-Cheng Liu, Yan Peng, Xue Hong, Hong-Hong Wang, Min-Min Zhang, Hong Liang. Synthesis, characterization, and in vitro antitumor properties of gold(III) compounds with the traditional Chinese medicine (TCM) active ingredient liriodenine. J. Biol. Inorg. Chem., 2012, 17(2), 247-261.
11．Zhen-Feng Chen*, Li Mao, Li-Min Liu, Yan-Cheng Liu,Yan Peng, Xue Hong, Hong-Hong Wang, Hua-Gang Liu, Hong Liang*. Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) matrine with Ga(III), Au(III), Sn(IV) ions, and DNA binding studies. J. Inorg. Biochem., 2011, 105, 171-180.
12．Zhen-Feng Chen*, Xiao-Yan Song, Yan Peng, Xue Hong, Yan-Cheng Liu, Hong Liang. High cytotoxicity of dihalo-substituted 8-quinolinolato-lanthanides. Dalton Trans., 2011, 40，1684-1692.
13． Zhen-Feng Chen*, Ming-Xiong Tan, Yan-Cheng Liu, Yan Peng, Hong-Hong Wang, Hua-Gang Liu and Hong Liang*. Synthesis, Characterization and Preliminary Cytotoxicity Evaluation of Five Lanthanide(III)-Plumbagin Complexes. J. Inorg. Biochem., 2011, 105，308-316.
14. Huang Tang, Li-Zhen Zhao, Hao-Tao Zhao, Shi-Liang Huang, Shu-Ming Zhong, Jiang-Ke Qin, Zhen-Feng Chen,* Zhi-Shu Huang, Hong Liang. Hybrids of oxoisoaporphine-tacrine congeners: Novel acetylcholinesterase and acetylcholinesterase- induced b-amyloid aggregation inhibitors. European Journal of Medicinal Chemistry, 2011, 46, 4970-4979.
15. Zhen-Feng Chen*, Hong Liang*, Progresses in TCM Metal-Based Antitumour Agents, Anti-Cancer Agents in Medicinal Chemistry, 2010, 10, 412-423.
16. Zhen-Feng Chen*, Yan-Cheng Liu, Li-Min Liu, Heng-Shan Wang, San-Hai Qin, Bo-Long Wang, He-Dong Bian, Bin Yang, Hoong-Kun Fun, Hua-Gang Liu, Hong Lian and Chris Orvig, Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) liriodenine with metal ions, and DNA binding studies, Dalton Trans.,2009,(2): 262-272.
17．Yan-Cheng Liu, Zhen-Feng Chen*, Li-Min Liu, Yan Peng, Xue Hong, Bin Yang,Hua-Gang Liu,Hong Liang and Chris Orvig, Divalent later transition metal complexes of the traditional chinese medicine (TCM) liriodenine: coordination chemistry, cytotoxicity and DNA binding studies, Dalton Trans., 2009, (48): 10813-10823.
18．Zhen-Feng Chen*, Ming-Xiong Tan, Li-Min Liu, Yan-Cheng Liu, Heng-Shan Wang,Bin Yang,Yan Peng, Hua-Gang Liu, Hong Liang and Chris Orvig, Cytotoxicity of the traditional chinese medicine (TCM) plumbagin in its copper chemistry, Dalton Trans.,2009, (48):10824-10833.
19．Meryn L. Bowen, Zhen-Feng Chen, Adrienne M. Roos, Ripen Misri, Urs Hafeli, Michael J. Adam and Chris Orvig, Long-chain rhenium and technetium glucosamine conjugates, Dalton Trans., 2009, 9228-9236.
20．Zhen-Feng Chen*, Shu-Feng Zhang, Hai-Sheng Luo, Brendan F. Abrahams and Hong Liang. Ni2(R*COO)4(4,4’-bipy)2----a robust homochrial quartz-like network with large chiral channels. CrystEngComm, 2007, 9, 7-29.
21. Zhen-Feng Chen*, Zhi-Li Zhang,Yu-Hui Tan,Yun-Zhi Tang,Hoong-Kun Fun, Zhong-Yuan Zhou, Brendan F. Abrahams and Hong Liang. Coordination polymers constructed by linking metal ions with azodibenzoate anions. CrystEngComm, 2008, 10, 17-231.
22. Zhi-Rong Qu, Zhen-Feng Chen*, et al. The first highly stable homochiral olefin-copper(I) 2D coordination polymer grid based on quinine as a building block.Organometallics, 2003，22，2814-2816.
23. Zhen-Feng Chen, Ren-Gen Xiong, Jing Zhang, Xue-Tai Chen, Zi-Ling Xue, Xiao-Zeng You. 2D molecular square grid with strong blue fluorescent emission: a complex of norfloxacin with Zinc(II). Inorganic Chemistry，2001，40(16)，4075-4077.
24. Zhen-Feng Chen, Ren-Gen Xiong, Abrahams Brendan F., Xiao-Zeng You, Chi-Ming Che. An unprecedented six-fold anion-type chiral diamondoid-like eight-coordinate Cd(II) coordination polymer with a second-order nonlinear optical effect. Dalton Trans, 2001，(17),2453-2455.
科研项目
1. 国家自然科学基金面上项目：雌激素靶向配体调控的高活性卤代喹啉-镧系系列抗肿瘤配合物（21271051），2013/1-2016/12，78万元。
2. 教育部创新团队项目:天然活性物质的发现、结构改造与功能（IRT1225）, 2013/1-2015/12，450万元。
3. 广西首批八桂学者项目:药物化学,2011/11-2016/10，500万元。
4.广西自然科学基金重点项目: 基于中药活性成分氧化阿朴菲生物碱抗肿瘤金属药物前期研究（2012GXNSFDA053005）, 2012/4-2014/3，25万元。

erliang

近日，自治区科协、自治区科技厅、自治区工信委、自治区人社厅、自治区国资委联合发布了《关于表彰首届广西创新争先奖和广西杰出工程师奖获奖者的决定》（桂科协组发〔2018〕15号），我校陈振锋教授与曾明华教授获得了首届广西创新争先奖。

获奖者陈振锋，近两年主持教育部“长江学者和创新团队发展计划”创新团队项目1项，广西自然科学创新团队项目1项，国家自然科学基金面上项目2项；近两年发表SCI论文22篇，获授权的发明专利5项，以第二完成人获得2017年广西科学技术特别贡献奖；应邀担任J. Med. Chem., Eur. J. Med. Chem.等20余种国际刊物审稿人和国家自然科学基金(医学部和化学部)通讯评委。获奖者曾明华，国家自然科学基金杰出青年科学基金获得者，近两年先后入选国家“万人计划”科技创新领军人才、中青年科技创新领军人才、全国优秀科技工作者；已主持和承担13项国家和省部级课题，作为第一完成人获得广西自然科学奖一等奖两次；在国际两大顶尖化学期刊J. Am. Chem. Soc.与Angew. Chem. Int. Ed.上各发表4篇论文，有8篇论文先后入选ESI高引频论文。

据悉，为了贯彻落实好全国“科技三会”精神和习近平总书记重要讲话精神，引领我区广大科技工作者在建设世界强国和工业强桂战略的进程中创新争先，自治区开展了首届广西创新争先奖和广西杰出工程师奖活动。该奖项主要面向近两年来在全区范围内的科技工作者团队和一线做出突出贡献的优秀科技工作者。本次活动评选出10个首届广西创新争先集体奖，30个首届广西创新争先个人奖，30个首届广西杰出工程师奖，并在广西科协第八次代表大会暨广西科协成立60周年纪念大会的开幕式上进行了颁奖。