广西师范大学化学与药学学院分析化学叶芳贵

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叶芳贵
联系方式
办公电话：13737700193
手机号码：13737700193
电子邮箱：fgye@mailbox.gxnu.edu.cn
办公地址：
基本介绍
叶芳贵，男，福建建瓯人，1974年生，博士，教授，博士生导师，广西自然科学杰出青年基金获得者。主要从事多孔材料的设计合成及其在色谱分析与纳米传感分析中的应用。先后主持国家自然科学基金3项、广西自然科学基金4项，科研成果获广西自然科学一等奖(第四完成人)及二等奖(第二完成人)各一项。迄今，以第一作者或通讯作者在Chem. Commun., Chem. Eur. J., J. Mater.Chem. B, J. Chromatogr. A, Anaylst, Sensor Actuat B-Chem., Microchimica Acta, RSC. Adv., New. J. Chem., J. Sep. Sci., Electrophoresis 等国内外权威刊物上发表SCI收录论文四十余篇,已获授权中国发明专利4项。
研究方向
1. 多孔材料（MOF、COF与整体柱）的设计合成及其在高效色谱分离及样品前处理中的应用;
2. 基于纳米模拟酶的传感体系构筑及其分析应用。
学历背景
2001.9～2006.7 福州大学化学化工学院分析化学专业硕博连读，博士
1993.9～1997.7 南开大学化学学院化学专业，本科
工作经历
2011.1～至今  广西师范大学化学与药学学院，教授
2007.1～2010.12 广西师范大学化学化工学院，副教授
2006.8～2006.12 广西师范大学化学化工学院，讲师
1997.8～2001.8 福州福抗药业集团股份有限公司，助理工程师
讲授课程
主讲分析化学、仪器分析、药物分析、分析化学前沿、表征技术及药物分析化学等课程。
论著专利
1. Haiguan Yang, Ruitao Yang, Peng Zhang, Yuemei Qin, Tao Chen and Fanggui Ye*. A bimetallic (Co/2Fe) metal-organic 1 framework with oxidase and peroxidase mimicking activity for colorimetric detection of hydrogen peroxide. Microchimica Acta 2017, DOI: 10.1007/s00604-017-2509-4
2. Tao Chen, Cong Zhang, Yuemei Qin, Haiguan Yang, Peng Zhang and Fanggui Ye*. Preparation of Cationic MOFs with mobile anions by anion stripping to remove 2,4-d from water. Materials 2017, 10, 879-890
3. Yuhao Xiong, Yuemei Qin, Linjing Su and Fanggui Ye*. Bioinspired synthesis of Cu2+-modified covalent triazine framework: A new highly efficient and promising peroxidase mimic. Chem. Eur. J. 2017, 23, 11037-11045
4. Jiannan Wang, Shufen Shen, Xin Lu and Fanggui Ye*. One-pot preparation of an organic polymer monolith by thiol-ene click chemistry for capillary electrochromatography. J. Sep. Sci. 2017, 40, 3144-3152
5. Haiguan Yang, Junqi Zha, Peng Zhang, Yuemei Qin, Tao Chen and Fanggui Ye*. Fabrication of CeVO4 as nanozyme for facile colorimetric discrimination of hydroquinone from resorcinol and catechol. Sensor Actuat. B-Chem. 2017, 247, 469-478
6. Fan Nie, Jiannan Wang, Xin Lu*, Fanggui Ye*. Preparation of bifunctional magnetic nanoparticles with octadecyl and phosphate group by thiol-ene click chemistry for extraction and enrichment of organophosphorus pesticides in tea drink. Anal. Methods 2017, 9, 2069-2075
7. Tao Chen, Yuhao Xiong, Yuemei Qin, Haiguan Yang, Peng Zhang and Fanggui Ye*. Facile synthesis of low-cost biomass-based γ-Fe2O3/C for efficient adsorption and catalytic degradation of methylene blue in aqueous solution. RSC Adv. 2017, 7, 336-343
8. Peng Zhang, Haiguan Yang, Tao Chen, Yuemei Qin, Fanggui Ye*. Facile one-pot preparation of a novel imidazolium-based monolith by thiol–ene click chemistry for capillary liquid chromatography. Electrophoresis DOI 10.1002/elps.201600288
9. Junyu Lu, Fanggui Ye*, Xiuxiang Huang, Lianqiang Wei, Dongmei Yao, Shengying Li, Miao Ouyang, Hongfang Lai. Ionic liquid-modified magnetic nanoparticles as solid phase extraction adsorbent coupled with HPLC for determination of linear alkylbenzene sulfonates in water samples. J. Sep. Sci. 2017, 40, 1133-1341
10. Haiguan Yang, Junqi Zha, Peng Zhang, Yuhao Xiong, Linjing Su and Fanggui Ye*. Sphere-like CoS with nanostructures as peroxidase mimics for colorimetric determination of H2O2 and mercury ions. RSC Adv. 2016, 6, 66963-66970
11. Peng Zhang, Jiannan Wang, Haiguang Yang, Linjing Su, Yuhao Xiong, Fanggui Ye*. Facile one-pot preparation of chiral monoliths with a well-defined framework based on thiol–ene click reaction for capillary liquid chromatography. RSC Adv. 2016, 6, 24835-24842
12. Linjing Su, Yuhao Xiong, Haiguan Yang, Peng Zhang, Fanggui Ye*. Prussian blue nanoparticles encapsulated inside a metal-organic framework via in situ growth as promising peroxidase mimetics for enzyme inhibitor screening. J. Mater. Chem. B 2016, 4, 128-134
13. Junyu Lu, Yuhao Xiong, Chunjin Liao, Fanggui Ye*. Colorimetric detection of uric acid in human urine and serum based on peroxidase mimetic activity of MIL-53(Fe). Anal. Methods 2015, 7, 9894-9899
14. Yuhao Xiong, Linjing Su, Haiguan Yang, Peng Zhang, Fanggui Ye*. Fabrication of copper sulfide using a Cu-based metal organic framework for colorimetric determination and efficient removal of Hg2+ in aqueous solutions. New J. Chem. 2015, 39, 9221-9227
15. Haiguan Yang, Yuhao Xiong, Peng Zhang, Linjing Su, Fanggui Ye*. Colorimetric detection of mercury ions using MnO2 nanorods as enzyme mimics. Anal. Methods 2015, 7, 4596-4601
16. Yuhao Xiong, Siheng Chen, Fanggui Ye*, Lingjing Su, Cong Zhang, Shufen Shen, Shulin Zhao. Synthesis of mixed valence state Ce-MOF as oxidase mimetics for colorimetric detection of biothiols. Chem. Commun. 2015, 51, 4635-4638
17. Shengchao Yang, Fanggui Ye*, Cong Zhang, Shufen Shen, Shulin Zhao. In situ synthesis of metal-organic frameworks in porous polymer monolith as stationary phase for capillary liquid chromatography. Analyst 2015, 140, 2755-2761
18. Cong Zhang, Fanggui Ye*, Shufen Shen, Yuhao Xiong, Linjing Su, Shulin Zhao. From metal-organic frameworks to magnetic nanostructured porous carbon composites: Towards highly efficient dye removal and degradation. RSC Adv. 2015, 5, 8228-8235
19. Yuhao Xiong, Fanggui Ye*, Cong Zhang, Shufen Shen, Linjing Su, Shulin Zhao. Synthesis of magnetic porous γ-Fe2O3/C@HKUST-1 composites for efficient removal of dyes and heavy metal ions from aqueous solution. RSC Adv. 2015, 5, 5164-5172
20. Yuhao Xiong, Siheng Chen, Fanggui Ye*, Linjing Su, Cong Zhang, Shufen Shen, Shulin Zhao. Preparation of magnetic core-shell nanoflowers Fe3O4@MnO2 as reusable oxidase mimetics for colorimetric detection of phenol. Anal. Methods 2015, 7, 1300-1306
21. Shufen Shen, Fanggui Ye*, Cong Zhang, Yuhao Xiong, Linjing Su and Shulin Zhao. Preparation of polyhedral oligomeric silsesquioxane based hybrid monoliths by thiol-ene click chemistry for capillary liquid chromatography. Analyst 2015, 140, 265-271
22. Shengchao Yang, Fanggui Ye*, Qinghui Lv, Cong Zhang, Shufen Shen, Shulin Zhao. Incorporation of metal-organic framework HKUST-1 into porous polymer monolithic capillary columns to enhance the chromatographic separation of small molecules. J. Chromatogr. A 2014, 1360, 143-149
23. Wei Yu, Chen Xia, Yang Sheng-Chao, LV Qing-Hui, Ye Fang-Gui*, Zhao Shu-Lin. Preparation and characterization of polymer solid-phase extraction monolith immobilized metal affinity ligands. Chin. J. Anal. Chem. 2014, 42, 495-500
24. Fanggui Ye, Jinwen Liu, Yong Huang, Shutin Li, Shulin Zhao∗. Competitive immunoassay of progesterone by microchipelectrophoresis with chemiluminescence detection. J. Chromatogr. B 2013, 936, 74-79
25. Fanggui Ye, Tinzhen Yang, Yong Huang, Shutin Li, Shulin Zhao*. Homogeneous immunoassay of cortisol based on microchip electrophoresis with chemiluminescence detection. Anal. Methods 2013, 5, 5657-5661
26. Aizhu Zhang, Fanggui Ye*, Junyu Lu, Shulin Zhao. Screening α-glucosidase inhibitor from natural products by capillary electrophoresis with immobilised enzyme onto polymer monolith modified by gold nanoparticles. Food Chem. 2013, 141, 1854-1859
27. Junyu Lu, Fanggui Ye*, Aizhu Zhang, Xia Chen, Yu Wei, Shulin Zhao. Preparation and evaluation of ionic liquid-gold nanoparticles functionalized silica monolithic column for capillary electrochromatography. Analyst 2012, 137, 5860-5865
28. Chen Xia, Wei Yu, Lu Jun-Yu, Zhang Ai-Zhu, Ye Fang-Gui*, Zhao Shu-Lin.  Preparation and evaluation of C18 modified capillary open-tubular column based on thiol-ene click chemistry for capillary electrochromatography. Chin. J. Anal. Chem. 2012, 40, 1584-1588.　
29. Junyu Lu, Fanggui Ye*, Aizhu Zhang, Zong Wei, Yan Peng, Shulin Zhao. Preparation and characterization of silica monolith modified with bovine serum albumin-gold nanoparticles conjugates and its use as chiral stationary phases for capillary electrochromatography. J. Sep. Sci. 2011, 34, 2329-2336
30. Zhang Ai-Zhu, Ye Fang-Gui*, Lu Jun-Yu, Wei Zong, Peng Yan, Zhao Shu-Lin. preparation and characterization of polymer solid-phase microextraction monolith modified with gold nanoparticle. Chin. J. Anal. Chem. 2011, 39, 1247-1250
31. Ye Fang-Gui*, Lu Jun-Yu, Wang Yuan, Zhang Ai-Zhu, Tian Jian-Niao, Zhao Shu-Lin. Preparation and characterization of gold nanoparticle-modified silica monolith for capillary electrochromatography. Chin. J. Anal. Chem. 2011, 39, 341-345
32. Fanggui Ye*, Baojun Huang, Shun Wang, Shulin Zhao. Electrochromatographic performance of conventional and polar-embedded C16 silica monolithic stationary phases. J. Sep. Sci. 2010, 33, 3386-3392
33. Fanggui Ye*, Hengshan Wang, Baojun Huang, Shulin Zhao. Maleopimaric acid anhydride-bonded silica monolith as chiral stationary phase for separations of phenylthiocarbamyl amino acids by capillary electrochromatography. Electrophoresis 2010, 31, 1488-1492
34. Fanggui Ye, Yong Huang, Qing Xu, Ming Shi, Shulin Zhao*. Quantification of taurine and amino acids in mice single fibrosarcoma cell by microchip electrophoresis coupled with chemiluminescence detection. Electrophoresis 2010, 31, 1630-1636
35. Fanggui Ye, Ming Shi, Yong Huang, Shulin Zhao*. Noncompetitive immunoassay for carcinoembryonic antigen in human serum by microchip electrophoresis for cancer diagnosis. Clin. Chim. Acta 2010, 411, 1058-1062
36. Ye Fang-gui*, Han Yan-yan, Wang Shun, Huang Bao-jun, Zhao Shu-lin. Preparation and characterization of butylaminopropyl silica monolithic column for capillary electrochromatography. Chin. J. Anal. Chem. 2010, 38, 192-196
37. Fanggui Ye*, Shun Wang, Shulin Zhao. Preparation and characterization of mixed-mode monolithic silica column for capillary electrochromatography. J. Chromatogr. A 2009, 1216, 8845-8850
38. Fanggui Ye, Shuting Li, Shulin Zhao*. Electrochromatographic evaluation of diol-bonded silica monolith capillary column for separation of basic compounds. J. Chromatogr. Sci. 2009, 47, 492-496
39. Fanggui Ye, Shuting Li, Shulin Zhao*. Development of a new C14 monolithic silica column containing embedded polar groups for pressurized capillary electrochromatography. J. Sep. Sci. 2007, 30, 3027-3034
40. Fanggui Ye, Zenghong Xie*, Xiaoping Wu, Xucong Lin. Determination of pyrethroid pesticide residues in vegetables by pressurized capillary electrochromatography. Talanta 2006, 69, 97-102
41. Fanggui Ye, Zenghong Xie*, Kwok-Yin Wong. Monolithic silica columns with mixed mode of hydrophilic interaction and weak anionexchange stationary phase for pressurized capillary electrochromatography. Electrophoresis 2006, 27, 3373-3380
42. Fanggui Ye, Zenghong Xie*, Xiaoping Wu, Xucong Lin, Guonan Chen. Separation of polar and basic compounds in hydrophilic interaction pressurized CEC using diethylenetriaminopropyl silica monolithic columns. Chromatographia 2006, 64, 267-272
43. Fanggui Ye, Zenghong Xie*, Xiaoping Wu, Xucong Lin, Guonan Chen*. Phenylaminopropyl silica monolithic column for pressure assisted capillary electrochromatography. J. Chromatogr. A 2006, 1117, 170-175
专利申请
1.叶芳贵,王恒山,赵书林,黄保军.硅胶毛细管整体手性固定相及其制备方法.中国发明专利，授权专利号：ZL200910114704.0
2.叶芳贵,陆俊宇,张爱珠,赵书林.离子液体硅胶毛细管整体柱固定相的制备方法.中国发明专利，授权专利号：ZL201110343311.4
3.叶芳贵,张爱珠,陆俊宇,赵书林.一种多孔整体柱固定化酶微反应器的制备方法.中国发明专利，授权专利号：ZL201110343288.9
4.叶芳贵,沈淑芬,张聪,赵书林.POSS杂化毛细管整体柱固定相及其制备方法，中国发明专利，授权专利号：ZL201410282354.X
5.赵书林,黄勇,叶芳贵,石明,李向堂.微流控芯片化学发光测定人单个血红细胞内物质的方法.中国发明专利, 授权专利号：ZL200910114403.8
科研项目
1.国家自然科学基金：点击反应制备分级孔金属-有机框架材料整体柱及其在富集和电色谱分离中的应用(21765002), 2018.1～2021.12, 主持；
2.国家自然科学基金：基于金属-有机骨架材料的磁性纳米粒子和整体柱的制备及用于多环芳烃电色谱分析研究（21365005)，2014.1～2017.12, 主持；
3.国家自然科学基金：在线亲和预富集芯片手性整体柱电色谱技术用于生物体内及单细胞中手性物质的分析研究(21065002),2011.1～2013.12, 主持(已结题)；
4.广西自然科学基金重点项目：基于MOF纳米酶的荧光传感平台构建及其用于有机磷农药残留分析, 2018.1～2021.12, 主持；
5.广西自然科学杰出青年基金：基于功能化MOFs膜涂层的磁性纳米粒子和电色谱整体柱的制备及其应用研究(2014GXNSFGA118002), 2014.6～2017.5，主持(已结题)；
6.广西自然科学基金面上项目：MOFs 聚合物毛细管固相微萃取整体柱的制备及其应用研究(2012GXNSFAA053024)，2012.1～2014.12，主持(已结题)；
7.广西自然科学基金应用基础专项：新型硅胶基质毛细管整体柱的制备及应用研究(0731004), 2007.5～2010.4，主持(已结题)；
8.广西医药产业人才小高地项目：磁性纳米粒子固定化酶微反应器的制备及其在广西特色中草药活性成分高通量筛选中的应用研究(1414)，2014.1～2016.12, 主持。
获奖情况
1. 2014年广西自然科学奖一等奖(排名第四)
2. 2010年广西自然科学奖二等奖(排名第二)
3. 2014年广西自然科学杰出青年基金获得者
4. 2013年入选广西师范大学拨尖人才