山西大学分子科学研究所王文明

kejibu

王文明，1988年11月出生。理学博士，山西大学分子科学研究所副教授，硕士生导师。2010年毕业于南开大学信息技术科学学院信息安全专业，获得工学学士学位。2015年毕业于南开大学生命科学学院，获得理学博士学位。博士期间多次赴日本高能加速研究机构进行学习交流。2015年7月进入山西大学分子科学研究所工作。


联系方式：
地址：太原市坞城路92号
单位：山西大学分子科学研究所
邮编：030006
邮箱：wangwm@sxu.edu.cn


主要研究方向：
蛋白质设计与自组装；
金属蛋白结构与功能研究。


代表性论文：
1. Wenming Wang, Lele Wang, Hai Chen, Jiachen Zang, Xuan Zhao, Guanghua Zhao, Hongfei Wang. Selective Elimination of the Key Subunit Interfaces Facilitates Conversion of Native 24-mer Protein Nanocage into 8‑mer Nanorings. Journal of the American Chemical Society, 2018, 140, 14078−14081.
2. Wenming Wang, Yaqin Zhao, Hongfei Wang, Binsheng Yang. Crystal structure of the trimeric N-terminal domain of ciliate Euplotes octocarinatus centrin binding with calcium ions. PROTEIN SCIENCE, 2018, 27, 1102-1108.
3. Wenming Wang, Fengmei Zhao, Yarui Zhao, Weiwei Pan, Pengcheng Cao, Lintao Wu , Zhijun Wang, Xuan Zhao, Yi Zhao, Hongfei Wang. Design, Synthesis, and Preliminary Bioactivity Evaluation of 2,7-Substituted Carbazole Derivatives as Potent Autotaxin Inhibitors and Antitumor Agents. Anti-Cancer Agents in Medicinal Chemistry, 2018, 18.
4. Xinyu Zhang, Wenming Wang, Chen Lia, Yi Zhaoc, Hong Yuand, Xianshi Tand, Lijie Wue, Zhuanhua Wanga, Hongfei Wang. Structural insights into the binding of buckwheat glutaredoxin with GSH and regulation of its catalytic activity. Journal of Inorganic Biochemistry, 2017, 173, 21–27.（共同第一作者）
5. Wenming Wang, Xiang Liu, Xu Wang, Hui Dong, Chao Ma, Jingmin Wang, Baocheng Liu,  Yonghong Mao, Ying Wang, Ting Li, Cheng Yang and Yu Guo. Structural and functional  diversity of nairovirus-encoded nucleoproteins. Journal of Virology. 2015, 89(23):11740-9.
6. Guo Yu, Wang Wenming, Sun Yuna, Ma Chao, Wang Xu, Wang Xin, Liu Pi，Shen Shu, Li Baobin, Lin Jianping, Deng Fei, Wang Hualin(*), Lou Zhiyong(*). Crystal structure of the core region of hantavirus nucleocapsid protein reveals the mechanism for ribonucleoprotein complex formation, Journal of Virology, 2015, 10(1128): 1048-1061.（共同第一作者）
7. Yu Guo, Wenming Wang, Wei Ji, Maping Deng, Yuna Sun, Honggang Zhou, Cheng Yang, Fei Deng, Hualin Wang, Zhihong Hu, Zhiyong Lou and Zihe Rao. Crimean-Congo hemorrhagic fever virus nucleoprotein reveals an endonuclease activity in the Bunyaviruses.  Proc Natl Acad Sci USA. 2012, 109, 13, 5046-51.（共同第一作者）
8. Kai Zhou, Jiachen Zang, Hai Chen, Wenming Wang, Hongfei Wang, and Guanghua Zhao. On-Axis Alignment of Protein Nanocage Assemblies from 2D to 3D through the Aromatic Stacking Interactions of Amino Acid Residues. ACS Nano, 2018, 12, 11323−11332.
9.    Zhang Shengli，Zang Jiachen，Wang Wenming，Chen Hai，Zhang Xiaorong，Wang Fudi，Wang Hongfei，Zhao Guanghua. Conversion of the Native 24-mer Ferritin Nanocage into Its Non-Native 16-mer Analogue by Insertion of Extra Amino Acid Residues. Angewandte Chemie-International Edition, 2016, 12, 55(52):16064-16070.