国家纳米科学中心刘晶

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刘晶，国家纳米科学中心研究员，博士生导师。2017年于国家纳米科学中心获博士学位，导师为陈春英研究员。2017-2021年在西北大学生命科学与医学部任教授。2021年3月加入国家纳米科学中心。2017年作为全国全学科20名代表之一参加诺贝尔奖获得者大会，2018年入选中国科协青年人才托举工程项目，2019年获得中国毒理学家资格认证。主要基于纳米材料的生物学效应与机制，针对肿瘤和感染等重大疾病的诊断和治疗设计智能纳米药物。近年来，在纳米生物医药、药理与毒理的国际重要期刊发表SCI论文40余篇，其中以第一/通讯作者在Adv Mater, Nano Today, ACS Nano, Small, Biomaterials等学术期刊发表论文16篇。


姓    名:刘晶       
性    别:女
职    务:无       
职    称:无
通讯地址:北京市海淀区中关村北一条11号
邮政编码:100190       
电子邮件:无       


研究领域：
纳米材料的免疫学效应与疾病治疗
基于磷脂膜的智能药物递送系统
纳米材料的毒理学机制与安全性评价


代表论著：
(1) Guo, Jin-Cheng#; An, Qiao#; Guo, Mengyu#; Xiao, Yating; Li, Bo; Gao, Fene; Wang, Yuqi; Li, Jiayang; Wang, Yaling; Liu, Ying; Meng, Huan; Guo, Jia; Liu, Jing*, Oxugen-independent free radical generation mediated by core-shell magnetic nanocomposites synergizes with immune checkpoint blockade for effective primary and metastatic tumor treatment, Nano Today, 2021, 36, 101024.
(2) Wang, Longwei#; Gao, Fene#; Wang, Aizhu; Chen, Xuanyu; Li, Hao; Zhang, Xiao; Zheng, Hong; Ji, Rui; Li, Bo; Yu, Xin*; Liu, Jing*; Gu, Zhanjun; Chen, Fulin; Chen, Chunying*, Defect-rich adhesive molybdenum disulfide/rGO vertical heterostructures with enhanced nanozyme activity for smart bacterial killing application, Advanced Materials, 2020, 2005423.
(3) Guo, Mengyu#; Zhang, Xiao#; Liu, Jing*; Gao, Fene; Zhang, Xiaolei; Hu, Xuhao; Li, Bo; Zhang, Xu; Zhou, Huige; Bai, Ru; Wang, Yaling; Li, Jiayang; Liu, Ying; Gu, Zhanjun; Chen, Chunying, Few-layer bismuthene for checkpoint knockdown enhanced cancer immunotherapy with rapid clearance and sequentially triggered one-for-all strategy, ACS Nano, 2020, 14, 15700-15713.
(4) Longwei Wang#; Xiao Zhang#; Xin Yu*; Fene Gao; Ziyi Shen; Xiaolei Zhang; Shenguang Ge; Jing Liu*; Zhanjun Gu; Chunying Chen*, An All-Organic Semiconductor C3N4/PDINH Heterostructure with Advanced Antibacterial Photocatalytic Therapy Activity, Advanced Materials, 2019, 1901965.
(5) Liu, Jing#; Zheng, Xiaopeng#; Yan, Liang; Zhou, Liangjun; Tian, Gan; Yin, Wenyan;Wang, Liming; Liu, Ying; Hu, Zhongbo; Gu, Zhanjun*; Chen, Chunying*; Zhao, Yuliang*, Bismuth Sulfide  Nanorods as a Precision Nanomedicine for in Vivo Multimodal Imaging-Guided Photothermal Therapy of Tumor, ACS Nano, 2015.1, 9(1): 696~707.
(6) Liu, Jing; Wang, Pengyang; Zhang, Xiao; Wang, Liming*; Wang, Dongliang; Gu, Zhanjun; Tang, Jinglong; Guo, Mengyu; Cao, Mingjing; Zhou, Huige; Liu, Ying*; Chen, Chunying*, Rapid Degradation and High Renal Clearance of Cu3BiS3 Nanodots for Efficient Cancer Diagnosis and Photothermal Therapy in Vivo, ACS Nano, 2016.4, 10(4): 4587~4598.
(7) Liu, Jing#; Kang, Seung-gu#; Wang, Peng; Wang, Yue; Lv, Xiaonan; Liu, Ying; Wang, Fei; Gu, Zonglin; Yang, Zaixing; Weber, Jeffrey K.; Tao, Ning; Qin, Zhihai; Miao, Qing; Chen, Chunying*; Zhou, Ruhong*; Zhao, Yuliang*, Molecular mechanism of Gd@C82(OH)(22) increasing collagen expression: Implication for encaging tumor, Biomaterials, 2018.1, 152: 24~36.
(8) Wang, Jing#; Liu, Jing#; Liu, Ying; Wang, Liming; Cao, Mingjing; Ji, Yinglu; Wu, Xiaochun; Xu, Yingying; Bai, Bing; Miao, Qing; Chen, Chunying; Zhao, Yuliang*, Gd-Hybridized Plasmonic Au-Nanocomposites Enhanced Tumor-Interior Drug Permeability in Multimodal Imaging-Guided Therapy, Advanced Materials, 2016.10.26, 28(40): 8950~8958.
(9) Liu, Jing#; Feng, Xiaoyan#; Chen, Zhiyun; Yang, Xiqin; Shen, Ziyi; Guo, Mengyu; Deng, Fangling; Liu, Ying*; Zhang, Heqiu*; Chen, Chunying*, The adjuvant e？ect of C60(OH)22 nanoparticles promoting both humoral and cellular immune responses to HCV recombinant proteins, Materials Science & Engineering C, 2019, 97: 753~759.
(10) Xu, Mengzhen#; Zhang, Can Yang#; Wu, Junguang; Zhou, Huige; Bai, Ru; Shen, Ziyi; Deng, Fangling; Liu, Ying*; Liu, Jing*, PEG-Detachable Polymeric Micelles Self-Assembled from Amphiphilic Copolymers for Tumor-Acidity-Triggered Drug Delivery and Controlled Release, ACS Applied Materials & Interfaces, 2019, 11: 5701~5713.
(11) An, Qiao#; Liu, Jing#; Yu, Meng; Wan, Jiaxun; Li, Dian; Wang, Changchun; Chen, Chunying*; Guo, Jia*, Multifunctional Magnetic Gd3+-Based Coordination Polymer Nanoparticles: Combination of Magnetic Resonance and Multispectral Optoacoustic Detections for Tumor-Targeted Imaging in vivo, Small, 2015.11.11, 11(42): 5675~5686. 17次
(12) Xu, Shuai#; Liu, Jing#; Li, Dian; Wang, Liming; Guo, Jia*; Wang, Changchun; Chen, Chunying*, Fe-salphen complexes from intracellular pH-triggered degradation of Fe3O4@Salphen-In-III CPPs for selectively killing cancer cells, Biomaterials, 2014.2, 35(5): 1676~1685.
(13) Huang, Sheng#; Liu, Jing#; He, Qian; Chen, Hongli; Cui, Jiabin; Xu, Suying; Zhao, Yuliang; Chen, Chunying*; Wang, Leyu*, Smart Cu1.75S nanocapsules with high and stable photothermal efficiency for NIR photo-triggered drug release, Nano Research, 2015.12, 8(12): 4038~4047.
(14) Xiao, Yating#; Liu, Jing#; Guo, Mengyu; Zhou, Huige; Jin, Jun; Liu, Jiaming; Liu, Ying; Zhang, Zhanjun*; Chen, Chunying*, Synergistic Combination Chemotherapy of Carrier-free Celastrol and Doxorubicin Nanocrystals for Overcoming Drug Resistance, Nanoscale, 2018, 10:12639.
(15) Yu, Xin*; Zhao, Zhenhuan*; Ren, Na; Liu, Jing*; Sun, Dehui; Ding, Longhua; Liu, Hong*, Top or Bottom, Assembling Modules Determine the Photocatalytic Property of the Sheetlike Nanostructured Hybrid Photocatalyst Composed with Sn3O4 and rGO (GQD), ACS Sustainable Chemistry and Engineering, 6:11775~11782.
(16) Wang, Song#; Zhang, Jianhua#; Wang, Huan; Yang, Lu; Hong, Shuai; Yu, Bo; Guo, Jincheng; Liu, Jing*; Zhu, Yanbing*, A novel multidimensional signature predicts prognosis in hepatocellular carcinoma patients, 2018, Journal of Cellular Physiology, 1-10.