上海科技大学刘一凡

taipingyang

刘一凡，上海科技大学物质科学与技术学院研究员，高通量生物技术实验室负责人，博士生导师。主要从事高通量生物技术、BT-IT新技术新方法研究，包括单细胞组学、高通量筛选、高通量检测技术等，相关成果于Nature Biomedical Engineering, ACS Nano等期刊发表。在成果转化方面，已申请专利6项，并联合创立了高探生物技术有限公司，获得高瓴资本独家天使轮融资。
       
刘一凡，助理教授
通讯地址：上海科技大学物质学院3号楼310-1
电子邮件：liuyf6@shanghaitech.edu.cn


2007.9-2011.6  上海交通大学，生物医学工程，学士
2011.8-2016.1  香港科技大学，电子与计算机工程，博士
2016.3-2017.12 美国加州大学旧金山分校，高通量生物学，博士后
2018.11 至今  上海科技大学物质学院，助理教授，研究员



主要论文
12. Lele Zhou, Rong Zhang, Hung-Ta Wang, Yifan Liu*. Polarity-dependent electro-wetting or -dewetting on a conductive silicon substrate. ARIXV/2022/4416280.
11. Chenguang Wang, Yi Xu, Shuainan Li, Yi Zhou, Qiuling Qiang, Yifan Liu and Xianqiang Mi*. Designer tetrahedral DNA framework-based microfluidic technology for multivalent capture and release of circulating tumor cells. Materials Today Bio, 2022.
10. Zhen Cao, Yuxin Ye, Guangyang Li, Rong Zhang, Shurong Dong* and Yifan Liu*. Monolithically integrated microchannel plate functionalized with ZnO nanorods for fluorescence-enhanced digital polymerase chain reaction. Biosensors and Bioelectronics, 2022. 新闻物质学院刘一凡课题组合作开发新型荧光增强数字PCR技术。
9. Chenwei Xiong, Jie Li, Luyao Li, Long Chen, Rong Zhang, Xianqiang Mi* and Yifan Liu*. Label-free electrical monitoring of nucleic acid amplification with integrated hydrogel ionic diodes. Materials Today Bio, 2022.
8. Jie Li#, Rong Zhang#, Ting Li, Qingyuan Shi, Zhangyue Song, Lichun Jiang, Yunfeng Shi, Conghui Ma, Xue Liang, Jingwei Zhang* and Yifan Liu*. Ultra-high-throughput microbial single-cell whole genome sequencing for genome-resolved metagnomics. BIORXIV/2022/485055.
7. Luyao Li#, Rong Zhang#, Xintong Tian, Ting Li, Bingchun Pu, Conghui Ma, Fang Ba, Chenwei Xiong, Yunfeng Shi, Jian Li*, Jingwei Zhang* and Yifan Liu*. Configurable Compartmentation Enables in vitro Reconstitution of Sustained Synthetic Biology Systems. BIORXIV/2022/484972.
6. Chen Sun, Leqian Liu, Liliana Pérez, Xiangpeng Li, Yifan Liu, Peng Xu, Eli A. Boritz, James I. Mullins, and Adam R. Abate. Droplet-microfluidics-assisted sequencing of HIV proviruses and their integration sites in cells from people on antiretroviral therapy. Nature Biomedical Engineering, 2022.
5. Binhong Hu, Yuqing Dong, Wenjing Zhou, Yichuan Ma, Luyao Li, Xianhua Fu, Wenxuan Zhang, Yuanyue Luo, Jingyu Pu, Xin Deng, Rong Zhang* and Songqing Liu*. Effect of Inonotus obliquus polysaccharide on composition of the intestinal flora in mice with acute endometritis. PLoS One, 2021.
4. Chenwei Xiong#, Boyin Zhang#, Rong Zhang and Yifan Liu*. An experimental and numerical study of polyelectrolyte hydrogel ionic diodes: towards electrical detection of charged biomolecules. Sensors, 21(24), 8279, 2021.
3. Bolin An, Yanyi Wang, Xiaoyu Jiang, Conghui Ma, Mark Mimee, Felix Moser, Ke Li, Xinyu Wang, Tzu-Chieh Tang, Yuanyuan Huang, Yifan Liu, Timothy K. Lu, ChaoZhong. Programming Living Glue Systems to Perform Autonomous Mechanical Repairs. Matter, 2020.
2. Conghui Ma, Jie Li, Boyin Zhang, Jingwei Zhang* and Yifan Liu*. Hydrogel microparticles functionalized with engineered Escherichia coli as living lactam biosensors. Sensors, 19，5556，2019.
1.Yifan Liu，Xuyue Chen, Yiqiu Zhang and Jian Liu. Advancing single-cell proteomics and metabolomics with microfluidic techniques. Analyst, 144, 846, 2018


11. Yifan Liu, Yushen Sheng, Lian Duan and Levent Yobas, “Two-dimensional hydrodynamic flow focusing in a microfluidic platform featuring a monolithic integrated glass micronozzle,” Applied Physics Letters, 109, 144101, 2016
10. Yifan Liu and Levent Yobas, “Slowing DNA translocation in a nanofluidic field-effect transistor,” ACS Nano, 10 (4), 3985-3994, 2016
9. Yifan Liu and Levent Yobas, “Microfluidic emulsification through a monolithic integrated glass micronozzle suspended inside a flow-focusing geometry,” Applied Physics Letters, 106, 174101, 2015
8. Yifan Liu and Levent Yobas, “Label-free specific detection of femtomolar cardiac troponin using an integrated nanoslit array fluidic diode,” Nano Letters, 14 (12), 6983–6990, 2014
7. Yifan Liu and Levent Yobas, “Label-free electrical quantification of amplified nucleic acids through nanofluidic diodes,” Biosensors and Bioelectronics, 50, 78-83, 2013
6. Yifan Liu and Levent Yobas, “Cylindrical glass nanocapillaries patterned via coarse lithography (> 1 μm) for biomicrofluidic applications,” Biomicrofluidics, 6 (4), 046502, 2013 (featured as Editor’s Pick)
5. Zhen Cao#, Luo Yuan#, Yifan Liu, Shuhuai Yao and Levent Yobas, “Microchannel plate electro-osmotic pump,” Microfluidics and Nanofluidics, 13(2), 279–288, 2012
4. L. Duan, Yifan Liu and L. Yobas, “Continuous-flow biomolecule separation through A 2D periodic array based on a glass capillary-well motif”, MicroTAS, 2016
3. Yifan Liu, et al., “Electrical protein sensing through a novel nanofluidic diode based on asymmetric nanoslits”, MicroTAS, 2014
2. Yifan Liu, et al., “On-chip generation of monodispersed emulsions independent of surface wettability through a suspended glass micronozzle”, Advances in Microfluidics & Nanofluidics, 2013
1. Yifan Liu, et al., “Stretching DNA in nanocapillaries fabricated through coarse lithography”, IISMM, 2013